Chloro(2-methylphenyl)[1,1'-bis(diphenylphosphino)ferrocene]nickel (II)

Chloro(2-methylphenyl)[1,1'-bis(diphenylphosphino)ferrocene]nickel (II) Property

Melting point:

173 °C

storage temp. 

2-8°C

form 

Powder

color 

yellow

Sensitive 

air sensitive

InChI

InChI=1S/2C17H11P.C7H7.ClH.Fe.Ni/c2*1-3-9-15(10-4-1)18(17-13-7-8-14-17)16-11-5-2-6-12-16;1-7-5-3-2-4-6-7;;;/h2*1-6,9-12,18H;2-5H,1H3;1H;;/q;;-1;;+2;/p-1

InChIKey

BNPFTYORGXHTBI-UHFFFAOYSA-M

SMILES

[Cl-][Ni+2]1([C-]2=CC=CC=C2C)P(C2C=CC=CC=2)(C2C=CC=CC=2)[C-]23C4=C5C6=C2[Fe+2]27893456C3C2=C7[C-]8(C9=3)P1(C1C=CC=CC=1)C1C=CC=CC=1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H341Suspected of causing genetic defects

H350May cause cancer

H360May damage fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

Chloro(2-methylphenyl)[1,1'-bis(diphenylphosphino)ferrocene]nickel (II) Chemical Properties,Usage,Production

General Description

(dppf)Ni(o-tolyl)Cl is an air stable reagent. Its crystal structure has been investigated by X-ray studies. (dppf)Ni(o-tolyl)Cl can be prepared from (Ph₃P)₂Ni(o-tolyl)Cl. It is widely employed as a precatalyst for various C-N bond formation reactions. Efficacy of (dppf)Ni(o-tolyl)Cl as a precatalyst for the amination of 4-n-butylchlorobenzene with morpholine under various optimized reaction conditions has been investigated.

reaction suitability

core: nickel
reaction type: Cross Couplings
reagent type: catalyst