N-(Azido-PEG4)-Biocytin

Product Name: N-(Azido-PEG4)-Biocytin
CAS No.: 2055042-70-9
Chemical Name: N-(Azido-PEG4)-Biocytin
Synonyms: N-(Azido-PEG4)-Biocytin
CBNumber: CB93363963
Molecular Formula: C27H47N7O9S
Formula Weight: 645.76858
MOL File: 2055042-70-9.mol

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N-(Azido-PEG4)-Biocytin Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DMF
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23286
Product name: N-(Azido-PEG4)-biocytin
Purity: 98%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-23286
Product name: N-(Azido-PEG4)-biocytin
Purity: 98%
Packaging: 500mg
Price: $840
Updated: 2021/12/16

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N-(Azido-PEG4)-Biocytin Chemical Properties,Usage,Production

Description

N-(Azido-PEG4)-biocytin is a biotin PEG linker containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound.

Uses

N-(Azido-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG4)-biocytin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG4)-Biocytin Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Azido-PEG4)-Biocytin Suppliers

China 19 United States 4 Global 23

Jinan elephant international trading co., LTD

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View Lastest Price from N-(Azido-PEG4)-Biocytin manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-(Azido-PEG4)-biocytin 2055042-70-9
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-30

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N-(Azido-PEG4)-Biocytin

2055042-70-9