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CC-671

Product Name
CC-671
CAS No.
1618658-88-0
Chemical Name
CC-671
Synonyms
CC-671;CS-2792;CC-671 (CC671;CC-671, 10 mM in DMSO;Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK;4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide;Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-
CBNumber
CB93364612
Molecular Formula
C28H28N6O4
Formula Weight
512.56
MOL File
1618658-88-0.mol
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CC-671 Property

Density 
1.351±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:60.0(Max Conc. mg/mL);117.06(Max Conc. mM)
form 
A crystalline solid
pka
12.12±0.50(Predicted)
color 
Off-white to light green
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
10mg
Price
$243
Updated
2024/03/01
TRC
Product number
C227915
Product name
CC-671
Packaging
10mg
Price
$1050
Updated
2021/12/16
ChemScene
Product number
CS-8218
Product name
CC-671
Purity
98.86%
Packaging
10mg
Price
$1068
Updated
2021/12/16
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CC-671 Chemical Properties,Usage,Production

Uses

CC-671, is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screen.

in vivo

CC-671 (compound 23) demonstrates significant tumor growth inhibition (TGI) ((vehicle -treated/vehicle) ×100%) of 71% at both 10 and 20 mg/kg on a every 3 days (q3d) dosing schedule. The body weight loss (BWL) in the CC-671 treated group (20 mg/kg ) is higher than in the 10 mg/kg group (17% vs 5%)[1].

IC 50

CLK2: 0.006 μM (IC50)

CC-671 Preparation Products And Raw materials

Raw materials

Preparation Products

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CC-671 Suppliers

China 49 United States 7 Global 56
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
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65
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
1250
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
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55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
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58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
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58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1991
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58

1618658-88-0, CC-671Related Search:


  • CC-671 (CC671
  • 4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide
  • CS-2792
  • CC-671
  • Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK
  • Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-
  • CC-671, 10 mM in DMSO
  • 1618658-88-0