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CC-671

Product Name
CC-671
CAS No.
1618658-88-0
Chemical Name
CC-671
Synonyms
CC-671;CS-2792;CC-671 (CC671;CC-671, 10 mM in DMSO;Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK;4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide;Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-
CBNumber
CB93364612
Molecular Formula
C28H28N6O4
Formula Weight
512.56
MOL File
1618658-88-0.mol
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CC-671 Property

Density 
1.351±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:60.0(Max Conc. mg/mL);117.06(Max Conc. mM)
form 
A crystalline solid
pka
12.12±0.50(Predicted)
color 
Off-white to light green
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
26184
Product name
CC-671
Packaging
10mg
Price
$243
Updated
2024/03/01
TRC
Product number
C227915
Product name
CC-671
Packaging
10mg
Price
$1050
Updated
2021/12/16
ChemScene
Product number
CS-8218
Product name
CC-671
Purity
98.86%
Packaging
10mg
Price
$1068
Updated
2021/12/16
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CC-671 Chemical Properties,Usage,Production

Uses

CC-671, is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor for the treatment of triple negative breast cancer initiated from a phenotypic screen.

in vivo

CC-671 (compound 23) demonstrates significant tumor growth inhibition (TGI) ((vehicle -treated/vehicle) ×100%) of 71% at both 10 and 20 mg/kg on a every 3 days (q3d) dosing schedule. The body weight loss (BWL) in the CC-671 treated group (20 mg/kg ) is higher than in the 10 mg/kg group (17% vs 5%)[1].

IC 50

CLK2: 0.006 μM (IC50)

CC-671 Preparation Products And Raw materials

Raw materials

Preparation Products

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CC-671 Suppliers

China 49 United States 7 Global 56
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1618658-88-0, CC-671Related Search:


  • CC-671 (CC671
  • 4-(4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3-methoxy-N-methylbenzamide
  • CS-2792
  • CC-671
  • Inhibitor,inhibit,Cyclin dependent kinase,CC671,CC-671,CC 671,CDK
  • Benzamide, 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-
  • CC-671, 10 mM in DMSO
  • 1618658-88-0