ENTEROSTATIN, HUMAN
- Product Name
- ENTEROSTATIN, HUMAN
- CAS No.
- 117830-79-2
- Chemical Name
- ENTEROSTATIN, HUMAN
- Synonyms
- APGPR Enterostatin;Human enterostatin;ALA-PRO-GLY-PRO-ARG;ALA-PRO-ASP-PRO-ARG;ENTEROSTATIN, HUMAN;H-ALA-PRO-GLY-PRO-ARG-OH;L-ALA-PRO-GLY-PRO-ARG SALT;Enterostatin , mouse, rat);H-ALA-PRO-GLY-PRO-ARG-OH ACOH;procolipase activation peptide
- CBNumber
- CB9336733
- Molecular Formula
- C21H36N8O6
- Formula Weight
- 496.56
- MOL File
- 117830-79-2.mol
ENTEROSTATIN, HUMAN Property
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble to 0.70 mg/ml in sterile water
- form
- Lyophilized solid.
- pka
- 3.60±0.21(Predicted)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- J66199
- Product name
- Enterostatin, human
- Packaging
- 10mg
- Price
- $167
- Updated
- 2021/12/16
- Product number
- J66199
- Product name
- Enterostatin, human
- Packaging
- 25mg
- Price
- $309
- Updated
- 2021/12/16
- Product number
- CS-0026705
- Product name
- Enterostatin(human,mouse,rat)
- Packaging
- 5mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- B5460
- Product name
- Enterostatin
- Packaging
- 5mg
- Price
- $297
- Updated
- 2021/12/16
- Product number
- CS-0026705
- Product name
- Enterostatin(human,mouse,rat)
- Packaging
- 1mg
- Price
- $80
- Updated
- 2021/12/16
ENTEROSTATIN, HUMAN Chemical Properties,Usage,Production
Definition
ChEBI: APGPR Enterostatin is a peptide.
Biological Activity
Enterostatin are pentapeptides that reduce fat intake.
in vitro
In the perfused ratpancreas, Enterostatin, at 100 mM, inhibits the insulin response to 9 mM glucose (by 70%), 0.1 mM tolbutamide (by 40%), and 5 mM arginine (by 70%).
in vivo
Chronically, enterostatin reduces fat intake, bodyweight, and body fat. This response may involve multiple metabolic effects of enterostatin, which include a reduction of insulin secretion, an increase in sympathetic drive to brown adipose tissue, and the stimulation of adrenal corticosteroid secretion. Enterostatin enhances memory consolidation after central or oral administration at a dose of 10 nmol/mouse or 300 mg/kg, respectively, in a step-through type passive avoidance test in mice. A dose of 38 nmol of enterostatin gives a significant inhibition of high-fat food intake, while at a higher dose of 76 nmol the inhibiting effect is lost. During the first hour, after injection of enterostatin, there is even a slight increase in food intake.
target
Human Endogenous Metabolite < span> |
ENTEROSTATIN, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ENTEROSTATIN, HUMAN manufacturers
- Product
- Enterostatin 117830-79-2
- Price
- US $0.00-0.00/mg
- Min. Order
- 1mg
- Purity
- 99%
- Supply Ability
- 10KG
- Release date
- 2021-09-16
- Product
- ENTEROSTATIN, HUMAN 117830-79-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05