m-PEG5-succinimidyl carbonate

Product Name: m-PEG5-succinimidyl carbonate
CAS No.: 1058691-00-1
Chemical Name: m-PEG5-succinimidyl carbonate
Synonyms: m-PEG5-succinimidyl carbonate;14-methoxy-3,6,9,12-tetraoxa tetradecanyl N-succinimidyl carbonate;2,5,8,11,14,17-Hexaoxaoctadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB93373663
Molecular Formula: C16H27NO10
Formula Weight: 393.39
MOL File: 1058691-00-1.mol

More

Less

m-PEG5-succinimidyl carbonate Property

Boiling point:: 469.3±55.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
form: Liquid
color: Colorless to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-23729
Product name: m-PEG5-succinimidylcarbonate
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-23729
Product name: m-PEG5-succinimidylcarbonate
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

More

Less

m-PEG5-succinimidyl carbonate Chemical Properties,Usage,Production

Description

m-PEG5-succinimidyl carbonate is a PEG linker with an attached succinumidyl carbonate group. The succinimidyl carbonate group is a good leaving group and commonly reacts with amine nucleophiles.

Uses

m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs; Alkyl/ether; Non-cleavable Linker

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

m-PEG5-succinimidyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

m-PEG5-succinimidyl carbonate Suppliers

China 17 United States 3 Global 20

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
Fax: 0086-571-81131109
Email: sales@huarongpharm.com
Country: CHINA
ProdList: 3148
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9990
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1994
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9681
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

1058691-00-1, m-PEG5-succinimidyl carbonateRelated Search:

m-PEG5-succinimidyl carbonate

2,5,8,11,14,17-Hexaoxaoctadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester

14-methoxy-3,6,9,12-tetraoxa tetradecanyl N-succinimidyl carbonate

1058691-00-1