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XDXWLKQMMKQXPV-PHYJMDTMSA-N

Product Name
XDXWLKQMMKQXPV-PHYJMDTMSA-N
CAS No.
1217230-31-3
Chemical Name
XDXWLKQMMKQXPV-PHYJMDTMSA-N
Synonyms
[13C4]-Eltrombopag;(E/Z)-Eltrombopag-13C4;Eltrombopag Impurity 47;XDXWLKQMMKQXPV-PHYJMDTMSA-N;[13C4]-Eltrombopag (Novartis number ETB115)
CBNumber
CB93406354
Molecular Formula
C25H22N4O4
Formula Weight
446.50258
MOL File
1217230-31-3.mol
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XDXWLKQMMKQXPV-PHYJMDTMSA-N Property

solubility 
Chloroform (Slightly), DMSO (Sparingly)
form 
Solid
color 
Light Orange to Orange
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E508002
Product name
Eltrombopag-13C4
Packaging
1mg
Price
$145
Updated
2021/12/16
TRC
Product number
E508002
Product name
Eltrombopag-13C4
Packaging
2.5mg
Price
$245
Updated
2021/12/16
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XDXWLKQMMKQXPV-PHYJMDTMSA-N Chemical Properties,Usage,Production

Uses

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

Biological Activity

(E/Z)-Eltrombopag 13C ((E/Z)-SB-497115 13C) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia[1].

References

[1]. Erickson-Miller CL, et al. Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist. Stem Cells. 2009 Feb;27(2):424-30.

XDXWLKQMMKQXPV-PHYJMDTMSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

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XDXWLKQMMKQXPV-PHYJMDTMSA-N Suppliers

China 14 India 3 United States 1 Global 18
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1217230-31-3, XDXWLKQMMKQXPV-PHYJMDTMSA-NRelated Search:

3'-aMino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid

  • XDXWLKQMMKQXPV-PHYJMDTMSA-N
  • [13C4]-Eltrombopag
  • Eltrombopag Impurity 47
  • [13C4]-Eltrombopag (Novartis number ETB115)
  • (E/Z)-Eltrombopag-13C4
  • 1217230-31-3