ChemicalBook > CAS DataBase List > 5-(4-METHYLPHENYL)-2-FUROIC ACID

5-(4-METHYLPHENYL)-2-FUROIC ACID

Product Name
5-(4-METHYLPHENYL)-2-FUROIC ACID
CAS No.
52938-98-4
Chemical Name
5-(4-METHYLPHENYL)-2-FUROIC ACID
Synonyms
AKOS BAR-0046;CHEMBRDG-BB 4401948;5-(4-METHYLPHENYL)-2-FUROIC ACID;5-P-TOLYL-FURAN-2-CARBOXYLIC ACID;5-(4-Tolyl)-furane-2-carboxylic acid;5-(4-Methylphenyl)-2-furoic acid 97%;5-(4-methylphenyl)-2-furancarboxylic acid;2-Furancarboxylic acid, 5-(4-methylphenyl)-;5-(4-methylphenyl)-2-furoic acid(SALTDATA: FREE);5-(4-Methylphenyl)furan-2-carboxylic acid, 2-Carboxy-5-(4-methylphenyl)furan, 4-(5-Carboxyfur-2-yl)toluene
CBNumber
CB9341706
Molecular Formula
C12H10O3
Formula Weight
202.21
MOL File
52938-98-4.mol
More
Less

5-(4-METHYLPHENYL)-2-FUROIC ACID Property

Melting point:
179-181 °C (lit.)
Boiling point:
374.6±30.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
3.21±0.10(Predicted)
form 
solid
Appearance
Light yellow to yellow Solid
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2932190090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
578223
Product name
5-(4-Methylphenyl)-2-furoic acid
Purity
97%
Packaging
1g
Price
$53.4
Updated
2023/01/07
SynQuest Laboratories
Product number
2H21-1-X7
Product name
5-(4-Methylphenyl)-2-furoic acid
Packaging
1g
Price
$64
Updated
2021/12/16
AK Scientific
Product number
X5449
Product name
5-(4-Methylphenyl)-2-furoic acid
Packaging
1g
Price
$82
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0026741
Product name
5-(4-METHYLPHENYL)-2-FUROIC ACID
Purity
95.00%
Packaging
1G
Price
$635.71
Updated
2021/12/16
AK Scientific
Product number
X5449
Product name
5-(4-Methylphenyl)-2-furoic acid
Packaging
250mg
Price
$37
Updated
2021/12/16
More
Less

5-(4-METHYLPHENYL)-2-FUROIC ACID Chemical Properties,Usage,Production

Synthesis

52939-04-5

52938-98-4

Step 3: Accurately weigh 310 mg (1.11 mmol) of the intermediate methyl 4-(4-methoxyphenyl)furan-2-carboxylate and add it slowly dropwise to a 5 mL methanol mixture containing 1 mL of 4 mol/L NaOH solution and heat to reflux for 3 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and concentrated to dryness under reduced pressure. The pH was adjusted to about 1 with 10% dilute hydrochloric acid and subsequently extracted three times with ethyl acetate. The organic phases were combined, washed twice with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 290 mg of the intermediate 5-(4-methoxyphenyl)furan-2-carboxylic acid in 100% yield.

References

[1] Patent: CN103992311, 2017, B. Location in patent: Paragraph 0103; 0137

5-(4-METHYLPHENYL)-2-FUROIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-(4-METHYLPHENYL)-2-FUROIC ACID Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Email
2853979819@qq.com
Country
China
ProdList
9998
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58

52938-98-4, 5-(4-METHYLPHENYL)-2-FUROIC ACIDRelated Search:


  • CHEMBRDG-BB 4401948
  • 5-P-TOLYL-FURAN-2-CARBOXYLIC ACID
  • AKOS BAR-0046
  • 5-(4-Tolyl)-furane-2-carboxylic acid
  • 5-(4-methylphenyl)-2-furoic acid(SALTDATA: FREE)
  • 5-(4-Methylphenyl)furan-2-carboxylic acid, 2-Carboxy-5-(4-methylphenyl)furan, 4-(5-Carboxyfur-2-yl)toluene
  • 5-(4-Methylphenyl)-2-furoic acid 97%
  • 5-(4-METHYLPHENYL)-2-FUROIC ACID
  • 5-(4-methylphenyl)-2-furancarboxylic acid
  • 2-Furancarboxylic acid, 5-(4-methylphenyl)-
  • 52938-98-4
  • Building Blocks
  • Furans
  • Heterocyclic Building Blocks
  • Building Blocks
  • Furans
  • Heterocyclic Building Blocks