5-(4-METHYLPHENYL)-2-FUROIC ACID
- Product Name
- 5-(4-METHYLPHENYL)-2-FUROIC ACID
- CAS No.
- 52938-98-4
- Chemical Name
- 5-(4-METHYLPHENYL)-2-FUROIC ACID
- Synonyms
- AKOS BAR-0046;CHEMBRDG-BB 4401948;5-(4-METHYLPHENYL)-2-FUROIC ACID;5-P-TOLYL-FURAN-2-CARBOXYLIC ACID;5-(4-Tolyl)-furane-2-carboxylic acid;5-(4-Methylphenyl)-2-furoic acid 97%;5-(4-methylphenyl)-2-furancarboxylic acid;2-Furancarboxylic acid, 5-(4-methylphenyl)-;5-(4-methylphenyl)-2-furoic acid(SALTDATA: FREE);5-(4-Methylphenyl)furan-2-carboxylic acid, 2-Carboxy-5-(4-methylphenyl)furan, 4-(5-Carboxyfur-2-yl)toluene
- CBNumber
- CB9341706
- Molecular Formula
- C12H10O3
- Formula Weight
- 202.21
- MOL File
- 52938-98-4.mol
5-(4-METHYLPHENYL)-2-FUROIC ACID Property
- Melting point:
- 179-181 °C (lit.)
- Boiling point:
- 374.6±30.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- pka
- 3.21±0.10(Predicted)
- form
- solid
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 578223
- Product name
- 5-(4-Methylphenyl)-2-furoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $53.4
- Updated
- 2023/01/07
- Product number
- 2H21-1-X7
- Product name
- 5-(4-Methylphenyl)-2-furoic acid
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- X5449
- Product name
- 5-(4-Methylphenyl)-2-furoic acid
- Packaging
- 1g
- Price
- $82
- Updated
- 2021/12/16
- Product number
- CHM0026741
- Product name
- 5-(4-METHYLPHENYL)-2-FUROIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $635.71
- Updated
- 2021/12/16
- Product number
- X5449
- Product name
- 5-(4-Methylphenyl)-2-furoic acid
- Packaging
- 250mg
- Price
- $37
- Updated
- 2021/12/16
5-(4-METHYLPHENYL)-2-FUROIC ACID Chemical Properties,Usage,Production
Synthesis
52939-04-5
52938-98-4
Step 3: Accurately weigh 310 mg (1.11 mmol) of the intermediate methyl 4-(4-methoxyphenyl)furan-2-carboxylate and add it slowly dropwise to a 5 mL methanol mixture containing 1 mL of 4 mol/L NaOH solution and heat to reflux for 3 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and concentrated to dryness under reduced pressure. The pH was adjusted to about 1 with 10% dilute hydrochloric acid and subsequently extracted three times with ethyl acetate. The organic phases were combined, washed twice with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 290 mg of the intermediate 5-(4-methoxyphenyl)furan-2-carboxylic acid in 100% yield.
References
[1] Patent: CN103992311, 2017, B. Location in patent: Paragraph 0103; 0137