2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

Product Name: 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
CAS No.: 287118-97-2
Chemical Name: 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
Synonyms: NCX 4040;NO-Aspirin;NO-ASPIRIN 2;2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester;2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester;2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID;Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester
CBNumber: CB9343492
Molecular Formula: C16H13NO7
Formula Weight: 331.28
MOL File: 287118-97-2.mol

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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Property

Melting point:: 83-86°C
Boiling point:: 495.7±40.0 °C(Predicted)
Density: 1.347±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble15mg/mL (clear solution)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 41-43
Safety Statements: 26-36/37-39
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0414
Product name: NCX 4040
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $110
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0414
Product name: NCX 4040
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $353
Updated: 2024/03/01

Tocris

Product number: 4531
Product name: NCX 4040
Purity: ≥98%(HPLC)
Packaging: 10
Price: $173
Updated: 2021/12/16

Tocris

Product number: 4531
Product name: NCX 4040
Purity: ≥98%(HPLC)
Packaging: 50
Price: $666
Updated: 2021/12/16

TRC

Product number: N633005
Product name: NO-Aspirin
Packaging: 250mg
Price: $1060
Updated: 2021/12/16

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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A novel nitric oxide-releasing aspirin,

Biochem/physiol Actions

NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Suppliers

Canada 1 China 27 India 1 United Kingdom 1 United States 5 Global 35

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287118-97-2, 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACIDRelated Search:

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

NO-ASPIRIN 2

NCX 4040

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

NO-Aspirin

2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester

2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester

Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester

287118-97-2

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