ChemicalBook > CAS DataBase List > 8-MERCAPTOGUANOSINE

8-MERCAPTOGUANOSINE

Product Name
8-MERCAPTOGUANOSINE
CAS No.
26001-38-7
Chemical Name
8-MERCAPTOGUANOSINE
Synonyms
8-SH-Guo;Nsc79216;SQ 12760;8-Tio-Guanosine;8-THIOGUANOSINE;8-MERCAPTOGUANOSINE;8-MERCAPTOGUANOSINE HYDRATE;7,8-dihydro-8-thioxoguanosine;8-Mercapto-7,8-dihydroguanosin;Guanosine, 7,8-dihydro-8-thioxo-
CBNumber
CB9347935
Molecular Formula
C10H13N5O5S
Formula Weight
315.31
MOL File
26001-38-7.mol
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8-MERCAPTOGUANOSINE Property

Melting point:
>220 °C
Density 
2.35±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly)
pka
6.15±0.20(Predicted)
form 
crystalline
color 
light yellow
Stability:
Hygroscopic
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Safety

WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T350788
Product name
8-Thioguanosine
Packaging
10mg
Price
$195
Updated
2021/12/16
Usbiological
Product number
296467
Product name
8-Thioguanosine
Packaging
5mg
Price
$340
Updated
2021/12/16
Biosynth Carbosynth
Product number
NT07601
Product name
8-Thioguanosine
Packaging
5mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
NT07601
Product name
8-Thioguanosine
Packaging
10mg
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
NT07601
Product name
8-Thioguanosine
Packaging
25mg
Price
$190
Updated
2021/12/16
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8-MERCAPTOGUANOSINE Chemical Properties,Usage,Production

Chemical Properties

Light yellow fine crystalline powder

Uses

8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll[1][2].

References

[1] Mond JJ, Hunter K, Kenny JJ, Finkelman F, Witherspoon K. 8-Mercaptoguanosine-mediated enhancement of in vivo IgG1, IgG2 and IgG3 antibody responses to polysaccharide antigens in normal and xid mice. Immunopharmacology. 1989 Nov-Dec;18(3):205-12. DOI:10.1016/0162-3109(89)90018-0
[2] Feldbush TL, Ballas ZK. Lymphokine-like activity of 8-mercaptoguanosine: induction of T and B cell differentiation. J Immunol. 1985 May;134(5):3204-11. PMID:3872330

8-MERCAPTOGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-MERCAPTOGUANOSINE Suppliers

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View Lastest Price from 8-MERCAPTOGUANOSINE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
8-MERCAPTOGUANOSINE 26001-38-7
Price
US $0.00-0.00/G
Min. Order
1G
Purity
97%
Supply Ability
2000
Release date
2025-06-04
Henan Aochuang Chemical Co.,Ltd.
Product
8-MERCAPTOGUANOSINE 26001-38-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26

26001-38-7, 8-MERCAPTOGUANOSINERelated Search:


  • 8-THIOGUANOSINE
  • 8-MERCAPTOGUANOSINE
  • 8-MERCAPTOGUANOSINE HYDRATE
  • 8-Mercapto-7,8-dihydroguanosin
  • Nsc79216
  • 7,8-dihydro-8-thioxoguanosine
  • SQ 12760
  • 8-Tio-Guanosine
  • Guanosine, 7,8-dihydro-8-thioxo-
  • 8-SH-Guo
  • 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-sulfanylidene-3,7-dihydropurin-6-one
  • 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-8,9-dihydro-1H-purin-6(7H)-one
  • 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-1,7,8,9-tetrahydro-6H-purin-6-one
  • 26001-38-7
  • C10H13N5O5S
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical