ChemicalBook > CAS DataBase List > 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

Product Name
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
CAS No.
51239-26-0
Chemical Name
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Synonyms
pCPT-cGMP;8-PCPT-CGMP NA;8-PCPT-CGMP TEA;CGMP, 8-PCPT-, NA;8-pCPT-cGMP, pCPT-cGMP;8-PCPT-CGMP SODIUM SALT;8-(4-Chlorophenylthio)guanosine3’8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono;8-(4-CHLOROPHENYLTHIO)GUANOSINE3':5'-CYC LIC MONOPH;8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT
CBNumber
CB5369780
Molecular Formula
C16H14ClN5NaO7PS
Formula Weight
509.79
MOL File
51239-26-0.mol
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8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Property

storage temp. 
-20°C
solubility 
H2O: 25 mg/mL
form 
powder
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5438
Product name
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
Purity
≥95% (HPLC), powder
Packaging
10mg
Price
$86.2
Updated
2024/03/01
Sigma-Aldrich
Product number
C5438
Product name
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
Purity
≥95% (HPLC), powder
Packaging
50mg
Price
$226.8
Updated
2024/03/01
TRC
Product number
C428843
Product name
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
Packaging
1mg
Price
$40
Updated
2021/12/16
TRC
Product number
C428843
Product name
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
Packaging
2.5mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
NC10430
Product name
8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt
Packaging
5mg
Price
$78.8
Updated
2021/12/16
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8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties,Usage,Production

Uses

8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs).

Definition

ChEBI: 8-(4-chlorophenylthio)-cGMP.Na is an organic sodium salt that is the monosodium salt of 8-(4-chlorophenylthio)-cGMP. It has a role as a protein kinase agonist. It contains an 8-(4-chlorophenylthio)-cGMP(1-).

Biochem/physiol Actions

Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist.

8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
NewCan Biotech Limited
Tel
+86-0571-86912261 +8613735419629
Email
sales@newcanbio.com
Country
China
ProdList
9980
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58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
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BOC Sciences
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16314854226
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1-631-614-7828
Email
inquiry@bocsci.com
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United States
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Energy Chemical
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021-58432009 400-005-6266
Fax
021-58436166
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marketing@energy-chemical.com
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China
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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+86-18521732826
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market@aladdin-e.com
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China
ProdList
48461
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Aladdin Scientific
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+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
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Carbosynth
Tel
--
Fax
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Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
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51239-26-0, 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALTRelated Search:


  • 8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono
  • 8-(4-chlorophenylthio)guanosine-3’,5’-cyclicmonophosphate(8-pcpt-cgmp),sodiumsalt
  • 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT
  • 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • 8-PCPT-CGMP NA
  • 8-PCPT-CGMP SODIUM SALT
  • 8-PCPT-CGMP TEA
  • CGMP, 8-PCPT-, NA
  • 8-(4-CHLOROPHENYLTHIO)GUANOSINE3':5'-CYC LIC MONOPH
  • 8-(4-Chlorophenylthio)-guanosine-3'',5''-cyclic monophosphoric acid sodium sa
  • 8-pCPT-cGMP, pCPT-cGMP
  • pCPT-cGMP
  • 8-(4-Chlorophenylthio)guanosine3&rsquo
  • 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • 51239-26-0
  • C16H14ClN5NaO7PS
  • C16H14ClN5O7PSNa
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Cyclic Nucleotide Metabolism
  • Cyclic Nucleotides and Analogs
  • G Proteins and Cyclic Nucleotides