8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Product Name
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- CAS No.
- 51239-26-0
- Chemical Name
- 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms
- pCPT-cGMP;8-PCPT-CGMP NA;8-PCPT-CGMP TEA;CGMP, 8-PCPT-, NA;8-pCPT-cGMP, pCPT-cGMP;8-PCPT-CGMP SODIUM SALT;8-(4-Chlorophenylthio)guanosine3’8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono;8-(4-CHLOROPHENYLTHIO)GUANOSINE3':5'-CYC LIC MONOPH;8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT
- CBNumber
- CB5369780
- Molecular Formula
- C16H14ClN5NaO7PS
- Formula Weight
- 509.79
- MOL File
- 51239-26-0.mol
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Property
- storage temp.
- -20°C
- solubility
- H2O: 25 mg/mL
- form
- powder
- color
- white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- C5438
- Product name
- 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
- Purity
- ≥95% (HPLC), powder
- Packaging
- 10mg
- Price
- $86.2
- Updated
- 2024/03/01
- Product number
- C5438
- Product name
- 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
- Purity
- ≥95% (HPLC), powder
- Packaging
- 50mg
- Price
- $226.8
- Updated
- 2024/03/01
- Product number
- C428843
- Product name
- 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
- Packaging
- 1mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- C428843
- Product name
- 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
- Packaging
- 2.5mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- NC10430
- Product name
- 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt
- Packaging
- 5mg
- Price
- $78.8
- Updated
- 2021/12/16
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties,Usage,Production
Uses
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs).
Definition
ChEBI: 8-(4-chlorophenylthio)-cGMP.Na is an organic sodium salt that is the monosodium salt of 8-(4-chlorophenylthio)-cGMP. It has a role as a protein kinase agonist. It contains an 8-(4-chlorophenylthio)-cGMP(1-).
Biochem/physiol Actions
Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist.