MYOSMINE

Product Name: MYOSMINE
CAS No.: 532-12-7
Chemical Name: MYOSMINE
Synonyms: Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-;MYOSIME;yosmine;MYSOMINE;MYOSMINE;Myosming;Brn 0119254;MYOSMINE(RG);Masmin, Masmin;WIDELY MYOSMINE
CBNumber: CB9354452
Molecular Formula: C9H10N2
Formula Weight: 146.19
MOL File: 532-12-7.mol

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MYOSMINE Property

Melting point:: 42-44°C
Boiling point:: 82-83°C 0,5mm
Density: 1.12±0.1 g/cm3(Predicted)
Flash point:: 82-83°C/0.5mm
storage temp.: 2-8°C
solubility: Methanol (Slightly), Water (Sparingly)
pka: pK1:5.26 (25°C)
form: Solid
color: Light Beige to Dark Yellow
BRN: 119254
Stability:: Moisture, Temperature Sensitive
LogP: 0.730 (est)
CAS DataBase Reference: 532-12-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: UT7660000
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 29399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M8765
Product name: Myosmine
Purity: ≥98%
Packaging: 100mg
Price: $112
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR3062
Product name: Nicotine Related Compound D
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50MG
Price: $507
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1463359
Product name: Myosmine
Packaging: 20mg
Price: $1450
Updated: 2024/03/01

Alfa Aesar

Product number: L11886
Product name: Myosmine, 98%, may contain up to 2% water
Packaging: 100mg
Price: $78
Updated: 2024/03/01

Alfa Aesar

Product number: L11886
Product name: Myosmine, 98%, may contain up to 2% water
Packaging: 500mg
Price: $282
Updated: 2024/03/01

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MYOSMINE Chemical Properties,Usage,Production

Description

The alkaloids found in tobacco smoke may be separated into those which are volatile in steam and those which are non-volatile. Myosmine occurs in the former group and, although only present in small quantities, is the most fully investigated of these bases. The alkaloid is normally obtained as an oily liquid which may be crystallized. It is optically inactive and readily soluble in light petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which, on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0- 17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole (picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of several products formed when nicotine is dehydrogenated over prepared quartz at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C.

Chemical Properties

Light Yellow Powder

Uses

mitogen

Uses

Tobacco alkaloid

Reactant for:
Nitrosation reactions
Peroxidation reaction with hydrogen peroxide

Uses

Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source.

Definition

ChEBI: Myosmine is a member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. It has a role as a plant metabolite, an EC 1.14.14.14 (aromatase) inhibitor and a mutagen. It is a pyrroline and a pyridine alkaloid.

Synthesis Reference(s)

Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094
The Journal of Organic Chemistry, 37, p. 1635, 1972
Tetrahedron Letters, 8, p. 5185, 1967

References

Spath, Wenusch, Zajic., Ber., 69, 393 (1936)
Woodward, Eisner, Haines., ibid, 69, 7S7 (1936)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)

MYOSMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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MYOSMINE Suppliers

Canada 1 China 183 Germany 2 Hungary 1 India 10 Japan 1 Switzerland 1 United Kingdom 8 United States 22 Global 229

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

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View Lastest Price from MYOSMINE manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: MYOSMINE 532-12-7
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2021-09-08

Hebei Mojin Biotechnology Co., Ltd

Product: MYOSMINE 532-12-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-06-25

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Myosmine 532-12-7
Price: US $2.30/Kg/Bag
Min. Order: 100g
Purity: 99%
Supply Ability: 20tons
Release date: 2021-12-09

532-12-7, MYOSMINERelated Search:

O-MYOSMINE NICOTINE IMP. D (EP): 3-(4,5-DIHYDRO-3H-PYRROL-2-YL)-PYRIDINE (MYOSMINE) MYOSMINE-D4 MYOSMINE(REAGENT / STANDARD GRADE) MYOSMINE, [PYRIDINE-5-3H]- 5-30 CI(0.185-1.11 TBQ)/MMOL, DELIVERED >= 96% PURE WITH HPLC RADIOCHROMATOGRAM MYOSMINE MYOSMINE-2,4,5,6-D4 (PYRIDINE-D4),MYOSMINE-2,4,5,6-D4 6-Methyl Myosmine MYOSMINE, [PYRIDINE-5-3H]- 3-(4,5-DIHYDRO-3H-PYRROL-2-YL)-QUINOLINE 2-Methyl Myosmine 5-METHYLMYOSMINE

3-[1-PYRROLIN-2-YL]PYRIDINE

3-(3,4-DIHYDRO-2H-PYRROL-5-YL)PYRIDINE

3-(4,5-DIHYDRO-3H-PYRROL-2-YL)PYRIDINE

MYOSIME

MYOSMINE

MYSOMINE

MYOSMINE(RG)

PYRIDINE,3-(1-PYRROLIN-2-YL)-

Brn 0119254

Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)- (9ci)

Myosmine, 98%, may contain up to 2% water

Nicotine Related Compound D (20 mg) (3-(4,5-dihydro-3H-pyrrol-2-yl)pyridine fumarate)

Nicotine EP Impurity D (myosmine )

2-(3-Pyridyl)-1-pyrroline

3-(1-pyrrolin-2-yl)-pyridin

Myosmine, 98%, from Nicotiana tabacum L.

NICOTINE RELATED COMPOUND D

MyosMine, froM Nicotiana tabacuM L.

Nicotine EP Impurity D

Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-

Nicotine Related Compound D (20 mg)

Nicotine EP Impurity D/ Nicotine Related Compound D (Myosmine)

WIDELY MYOSMINE

Myosming

yosmine

Nicotine USP Related Compound D

3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine (Myosmine)

3-(4,5-dihydro-3H-pyrrol-2-yl)pyridine (myosmine)

Nicotine Impurity D

Nicotine Intermediates MYOSMINE

Masmin, Masmin

Acamprosate Impurity 7

532-12-7

Pyridines

Heterocyclic Building Blocks

Building Blocks

C9 to C46

Amines

Alkaloids

Nicotine Derivatives

Heterocycles

532-12-7