MYOSMINE
- Product Name
- MYOSMINE
- CAS No.
- 532-12-7
- Chemical Name
- MYOSMINE
- Synonyms
- Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-;MYOSIME;yosmine;MYSOMINE;MYOSMINE;Myosming;Brn 0119254;MYOSMINE(RG);WIDELY MYOSMINE;Nicotine Impurity D
- CBNumber
- CB9354452
- Molecular Formula
- C9H10N2
- Formula Weight
- 146.19
- MOL File
- 532-12-7.mol
MYOSMINE Property
- Melting point:
- 42-44°C
- Boiling point:
- 82-83°C 0,5mm
- Density
- 1.12±0.1 g/cm3(Predicted)
- Flash point:
- 82-83°C/0.5mm
- storage temp.
- 2-8°C
- solubility
- Methanol (Slightly), Water (Sparingly)
- pka
- pK1:5.26 (25°C)
- form
- Solid
- color
- Light Beige to Dark Yellow
- BRN
- 119254
- Stability:
- Moisture, Temperature Sensitive
- LogP
- 0.730 (est)
- CAS DataBase Reference
- 532-12-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- UT7660000
- HazardClass
- IRRITANT, IRRITANT-HARMFUL
- HS Code
- 29399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M8765
- Product name
- Myosmine
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $112
- Updated
- 2024/03/01
- Product number
- PHR3062
- Product name
- Nicotine Related Compound D
- Purity
- certified reference material, pharmaceutical secondary standard
- Packaging
- 50MG
- Price
- $507
- Updated
- 2024/03/01
- Product number
- 1463359
- Product name
- Myosmine
- Packaging
- 20mg
- Price
- $1450
- Updated
- 2024/03/01
- Product number
- L11886
- Product name
- Myosmine, 98%, may contain up to 2% water
- Packaging
- 100mg
- Price
- $78
- Updated
- 2024/03/01
- Product number
- L11886
- Product name
- Myosmine, 98%, may contain up to 2% water
- Packaging
- 500mg
- Price
- $282
- Updated
- 2024/03/01
MYOSMINE Chemical Properties,Usage,Production
Description
The alkaloids found in tobacco smoke may be separated into those which are volatile in steam and those which are non-volatile. Myosmine occurs in the former group and, although only present in small quantities, is the most fully investigated of these bases. The alkaloid is normally obtained as an oily liquid which may be crystallized. It is optically inactive and readily soluble in light petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which, on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0- 17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole (picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of several products formed when nicotine is dehydrogenated over prepared quartz at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C.
Chemical Properties
Light Yellow Powder
Uses
mitogen
Uses
Tobacco alkaloid
Reactant for:
Nitrosation reactions
Peroxidation reaction with hydrogen peroxide
Uses
Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source.
Definition
ChEBI: Myosmine is a member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. It has a role as a plant metabolite, an EC 1.14.14.14 (aromatase) inhibitor and a mutagen. It is a pyrroline and a pyridine alkaloid.
Synthesis Reference(s)
Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094
The Journal of Organic Chemistry, 37, p. 1635, 1972
Tetrahedron Letters, 8, p. 5185, 1967
References
Spath, Wenusch, Zajic., Ber., 69, 393 (1936)
Woodward, Eisner, Haines., ibid, 69, 7S7 (1936)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)
MYOSMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from MYOSMINE manufacturers
- Product
- Myosmine 532-12-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.91%
- Supply Ability
- 200000
- Release date
- 2024-04-22
- Product
- MYOSMINE 532-12-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-06-25
- Product
- Myosmine 532-12-7
- Price
- US $85.00/KG
- Min. Order
- 1KG
- Purity
- 99.%
- Supply Ability
- 10 ton
- Release date
- 2021-12-17