ChemicalBook > CAS DataBase List > 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid

Product Name
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
CAS No.
683808-78-8
Chemical Name
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
Synonyms
Poloppin;Poloppin >=98% (HPLC);1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-;3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
CBNumber
CB93698449
Molecular Formula
C20H15BrF3NO2
Formula Weight
438.2378096
MOL File
683808-78-8.mol
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Property

Boiling point:
536.7±50.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
pka
4.62±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2186
Product name
Poloppin
Purity
≥98% (HPLC)
Packaging
5MG
Price
$81.3
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2186
Product name
Poloppin
Purity
≥98% (HPLC)
Packaging
25MG
Price
$411
Updated
2024/03/01
ChemScene
Product number
CS-0087610
Product name
Poloppin
Packaging
5mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0087610
Product name
Poloppin
Packaging
10mg
Price
$340
Updated
2021/12/16
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Chemical Properties,Usage,Production

Description

Poloppin is a modulator of protein-protein interactions of the mitotic polo-like kinases. It acts by targeting mutant KRAS, working synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.

3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Suppliers

Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9708
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9854
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8618
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24017
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32715
Advantage
60

683808-78-8, 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acidRelated Search:


  • 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
  • Poloppin
  • Poloppin >=98% (HPLC)
  • 1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-
  • 683808-78-8