ChemicalBook > CAS DataBase List > 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
- Product Name
- 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
- CAS No.
- 683808-78-8
- Chemical Name
- 3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
- Synonyms
- Poloppin;Poloppin >=98% (HPLC);1H-Pyrrole-2-propanoic acid, 5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-;3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid
- CBNumber
- CB93698449
- Molecular Formula
- C20H15BrF3NO2
- Formula Weight
- 438.2378096
- MOL File
- 683808-78-8.mol
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Property
- Boiling point:
- 536.7±50.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 4.62±0.10(Predicted)
- form
- powder
- color
- white to beige
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2186
- Product name
- Poloppin
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $81.3
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2186
- Product name
- Poloppin
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $411
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-0087610
- Product name
- Poloppin
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087610
- Product name
- Poloppin
- Packaging
- 10mg
- Price
- $340
- Updated
- 2021/12/16
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Chemical Properties,Usage,Production
Description
Poloppin is a modulator of protein-protein interactions of the mitotic polo-like kinases. It acts by targeting mutant KRAS, working synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid Suppliers
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