Structure
ChemicalBook > CAS DataBase List > 5-Chloro-6-hydroxynicotinic Acid

5-Chloro-6-hydroxynicotinic Acid

Structure
Product Name
5-Chloro-6-hydroxynicotinic Acid
CAS No.
54127-63-8
Chemical Name
5-Chloro-6-hydroxynicotinic Acid
Synonyms
TIMTEC-BB SBB003814;Avatrombopag Impurity 53;Nicotinic Acid Impurity 16;oro-6-hydroxynicotinic Acid;5-Chloro-6-hydroxynicotinicaci;5-CHLORO-6-HYDROXYNICOTINIC ACID;5-Chloro-6-hydroxynicotinicacid,98%;5-Chloro-6-hydroxynicotinic acid 98%;5-Chloro-6-hydroxynicotinic Acid >5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID
CBNumber
CB9399994
Molecular Formula
C6H4ClNO3
Formula Weight
173.55
MOL File
54127-63-8.mol
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5-Chloro-6-hydroxynicotinic Acid Property

Melting point:
≥300 °C(lit.)
Boiling point:
334.6±42.0 °C(Predicted)
Density 
1.4914 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
3.38±0.50(Predicted)
color 
White to Light yellow to Light orange
CAS DataBase Reference
54127-63-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C1758
Product name
5-Chloro-6-hydroxynicotinic Acid
Purity
>95.0%(GC)(T)
Packaging
5g
Price
$19
Updated
2025/07/31
TRC
Product number
C422058
Product name
5-Chloro-6-hydroxynicotinic Acid
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
C422058
Product name
5-Chloro-6-hydroxynicotinic Acid
Packaging
100mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
F802
Product name
5-Chloro-6-hydroxynicotinic Acid
Packaging
5g
Price
$25
Updated
2021/12/16
Matrix Scientific
Product number
002128
Product name
3-Chloro-2-hydroxypyridine-5-carboxylic acid
Purity
97%
Packaging
1g
Price
$9
Updated
2021/12/16
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5-Chloro-6-hydroxynicotinic Acid Chemical Properties,Usage,Production

Structure

5-Chloro-6-hydroxynicotinic Acid (5Cl6HNA) was recrystallized four times from ethanol at 345 K. The obtained white crystalline solid was first dried in a vacuum at 1.3 Pa and 353 K. The crystals were then ground with a mortar and a pestle and further dried for 24 h at 1.3 Pa and 353 K. The powder pattern obtained at 295 ± 1 K was indexed as monoclinic, space group P21/c, with a= 5.478 Å, b= 10.545 Å, c= 11.796 Å, β=97.76°. These results are in agreement with those obtained in this work from single crystal X-ray diffraction experiments carried out at 293 ±2K(P21/c, a ) 5.469 Å, b = 10.529 Å, c= 11.795 Å, β= 97.72°). DSC (fusion, β= 2 K ·min-1 ): Ton= 582.2 K and Tmax= 585.6 K[1].

Chemical Properties

white to beige fine crystalline powder

References

[1] Rui C. Santos. “Energetics and Structure of Hydroxynicotinic Acids. Crystal Structures of 2-, 4-, 6-Hydroxynicotinic and 5-Chloro-6-hydroxynicotinic Acids.” The Journal of Physical Chemistry B 113 43 (2009): 14291–14309.

5-Chloro-6-hydroxynicotinic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-6-hydroxynicotinic Acid Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 5-Chloro-6-hydroxynicotinic Acid manufacturers

R&D Scientific Inc.
Product
5-chloro-6-hydroxynicotinic acid 54127-63-8
Price
US $780.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-19
Hebei Zhanyao Biotechnology Co. Ltd
Product
5-Chloro-6-hydroxy-3-pyridinecarboxylic acid 54127-63-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 TONS
Release date
2021-10-15
Dideu Industries Group Limited
Product
5-Chloro-6-hydroxy-3-pyridinecarboxylic acid 54127-63-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-22

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