ChemicalBook > CAS DataBase List > Lopinavir EP impurity Q
Lopinavir EP impurity Q
- Product Name
- Lopinavir EP impurity Q
- CAS No.
- 667904-94-1
- Chemical Name
- Lopinavir EP impurity Q
- Synonyms
- Lopinavir Impurity 17;Lopinavir EP impurity Q;Lopinavir Impurity 17（Lopinavir EP Impurity Q）;Acetamide, N,N'-[(1S,2S,4S)-2-hydroxy-1,4-bis(phenylmethyl)-1,4-butanediyl]bis[2-(2,6-dimethylphenoxy)-;N-[(1S,2S,4S)-1-benzyl-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-2-hydroxy-5-phenylpentyl]-2-(2,6-dimethylphenoxy)acetamide,
- CBNumber
- CB94033593
- Molecular Formula
- C38H44N2O5
- Formula Weight
- 608.77
- MOL File
- 667904-94-1.mol
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Lopinavir EP impurity Q Property
- Boiling point:
- 864.5±65.0 °C(Predicted)
- Density
- 1.154±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator (0°C)
- solubility
- Chloroform; Dichloromethane; DMSO; Ethyl Acetate; Methanol
- pka
- 13.89±0.46(Predicted)
- form
- Solid
- color
- White
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Lopinavir EP impurity Q Chemical Properties,Usage,Production
Uses
N,N''-2-Hydroxy-1,4-bis(phenylmethyl)-2,6-dimethylphenoxy)acetamide is a by-product from the synthesis of (αS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide (Lopinavir EP Impurity R) (D476505), an impurity of Lopinavir (L469480), a selective HIV protease inhibitor.
Lopinavir EP impurity Q Preparation Products And Raw materials
Raw materials
Preparation Products
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667904-94-1, Lopinavir EP impurity QRelated Search:
N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6-dimethylphenoxy)acetamide
Lopinavir
(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
(2,6-Xylyloxy)acetyl Lopinavir
(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide
Lopinavir EP impurity P
Lopinavir EP impurity K
(2S)-N-[(2S,4R,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
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