PHENCYCLIDINE HYDROCHLORIDE Property

Melting point:

233-235°C

Boiling point:

135-137°C

storage temp. 

Store at RT

solubility 

H₂O: 11.2 mg/mL

form 

Solid

color 

Crystals

Water Solubility 

Soluble to 40 mM in water

EPA Substance Registry System

Piperidine, 1-(1-phenylcyclohexyl)-, hydrochloride (956-90-1)

Safety

Hazard Codes 

T

Risk Statements 

25

Safety Statements 

36/37-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

TN2272600

HazardClass 

6.1(a)

PackingGroup 

I

HS Code 

2933330000

Toxicity

LD50 orally in mice: 76.5 mg/kg (Bailey)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H336May cause drowsiness or dizziness

PHENCYCLIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Phencyclidine hydrochloride (PCP) is a psychoactive drug that has inhibitory, excitatory, analgesic and hallucinogenic effects on the central nervous system. Its chemical name is 1-(1-phenylcyclohexane)piperidine. It is a dissociative drug once used by anesthesiologists as an anesthetic with hallucinogenic and neurotoxic effects.

Chemical Properties

Crystalline Solid

Uses

Controlled substance (depressant). Anesthetic (intravenous).

Uses

Anesthetic (intravenous). Controlled substance (depressant).

brand name

Sernylan (Parke-Davis).

Biological Activity

Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.

Biochem/physiol Actions

σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime

storage

Store at RT