I-BET 151 hydrochloride

Product Name: I-BET 151 hydrochloride
CAS No.: 1883545-47-8
Chemical Name: I-BET 151 hydrochloride
Synonyms: I-BET 151 2HCl;I-BET 151 hydrochloride;I-BET 151 dihydrochloride;I BET151 dihydrochloride,I-BET-151 dihydrochloride,IBET151 dihydrochloride;7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
CBNumber: CB94189029
Molecular Formula: C23H22ClN5O3
Formula Weight: 451.91
MOL File: 1883545-47-8.mol

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I-BET 151 hydrochloride Property

storage temp.: Store at -20°C
solubility: insoluble in H2O; ≥22.05 mg/mL in EtOH; ≥31.7 mg/mL in DMSO
form: solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4650
Product name: I-BET151dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $255
Updated: 2021/12/16

Tocris

Product number: 4650
Product name: I-BET151dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $1045
Updated: 2021/12/16

TRC

Product number: I120058
Product name: I-BET151Dihydrochloride
Packaging: 1mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BI162773
Product name: I-BET 151 dihydrochloride
Packaging: 10mg
Price: $145
Updated: 2021/12/16

ApexBio Technology

Product number: B5670
Product name: I-BET151hydrochloride
Packaging: 5mg
Price: $96
Updated: 2021/12/16

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I-BET 151 hydrochloride Chemical Properties,Usage,Production

Biological Activity

i-bet 151 dihydrochloride is a bet bromodomain inhibitor that prevents bet from recruiting to chromatin. i-bet 151 induces mll-fusion leukemia cell line apoptosis and g0 / g1 cell cycle arrest in vitro, and reduces bcl2 expression in nomo1 cells. i-bet 151 improves the survival rate of two kinds of mll fusion leukemia mice, and enhances the differentiation of human ipscs into megakaryocytes.[1]. malherbe p, masciadri r, norcross r d, et al. characterization of (r,s)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3h-benzofuran-2-one as a positive allosteric modulator of gabab receptors. british journal of pharmacology, 2008, 154(4): 797.

storage

-20°C

I-BET 151 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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I-BET 151 hydrochloride Suppliers

China 16 United Kingdom 1 United States 3 Global 20

ShangHai Biochempartner Co.,Ltd

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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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MedBioPharmaceutical Technology Inc

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Jinan Jiuli Biotechnology Co. , Ltd.

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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Shaanxi Xihua Chemical Industry Co., Ltd

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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1883545-47-8, I-BET 151 hydrochlorideRelated Search:

I-BET 151 hydrochloride

7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride

I-BET 151 dihydrochloride

I BET151 dihydrochloride,I-BET-151 dihydrochloride,IBET151 dihydrochloride

I-BET 151 2HCl

1883545-47-8