NICOTINE SALICYLATE Property

Melting point:

112-1150C

alpha 

D20 +13° (c = 9)

Density 

1.27 g/cm3

solubility 

DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

EPA Substance Registry System

Benzoic acid, 2-hydroxy-, compd. with 3-[(2S)-1-methyl-2-pyrrolidinyl]pyridine (1:1) (29790-52-1)

Safety

RIDADR 

1657

HazardClass 

6.1(a)

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

NICOTINE SALICYLATE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Nicotine Salicylate is used for treatment of smoking withdrawal syndrome.

General Description

A white crystalline solid. Combustible. Toxic by inhalation (dust, etc.) and may be toxic by skin absorption. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Soluble in water

Reactivity Profile

Nicotine-An alkaloid produced from tobacco. Colorless, oily liquid, combustible, highly toxic. When heated to decomposition NICOTINE SALICYLATE emits very toxic fumes of carbon monoxide and oxides of nitrogen [Lewis, 3rd ed., 1993, p. 919].

Health Hazard

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Safety Profile

A poison. Symptoms of exposure: extreme nausea, vomiting, evacuation of bowel and bladder, mental confusion, twitching, convulsions. Base is ready absorbed through mucous membranes and intact skin. Institute treatment immedately. When heated to decomposition it emits toxic fumes of NOx and CO. See also NICOTINE.