(+/-)-NICOTINE

Product Name: (+/-)-NICOTINE
CAS No.: 22083-74-5
Chemical Name: (+/-)-NICOTINE
Synonyms: NICOTINE;(r,s)-nicotine;rac-Nicotine;1-METHYL-2-(3-PYRIDYL)PYRROLIDINE;Nicotine for system suitability CRS;dl-nicotine;(+-)-pyridin;(+-)-nicotin;BLACK LEAF 40;(+/-)-NICOTINE
CBNumber: CB2459639
Molecular Formula: C10H14N2
Formula Weight: 162.23
MOL File: 22083-74-5.mol

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(+/-)-NICOTINE Property

Melting point:: -79 °C
Boiling point:: 67°C/0.5 mm
Density: 1.02 g/mL at 25 °C(lit.)
Flash point:: 101 °C
storage temp.: Refrigerator
solubility: ethanol: 50 mg/mL
form: liquid
pka: 8.02(at 25℃)
color: yellow
optical activity: [α]25/D 0°(lit.)
BRN: 82108
Stability:: Air Sensitive
CAS DataBase Reference: 22083-74-5(CAS DataBase Reference)

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Safety

Hazard Codes: T+,N
Risk Statements: 25-27-51/53
Safety Statements: 36/37-45-61
RIDADR: UN 1654 6.1/PG 2
WGK Germany: 3
RTECS: QS5257500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N0267
Product name: (±)-Nicotine
Purity: ≥99% (TLC), liquid
Packaging: 100mg
Price: $119
Updated: 2024/03/01

Sigma-Aldrich

Product number: N0267
Product name: (±)-Nicotine
Purity: ≥99% (TLC), liquid
Packaging: 1g
Price: $756
Updated: 2024/03/01

Cayman Chemical

Product number: 16535
Product name: (±)-Nicotine
Purity: ≥98%
Packaging: 100mg
Price: $101
Updated: 2024/03/01

Cayman Chemical

Product number: 16535
Product name: (±)-Nicotine
Purity: ≥98%
Packaging: 250mg
Price: $177
Updated: 2024/03/01

Sigma-Aldrich

Product number: N0267
Product name: (±)-Nicotine
Purity: ≥99% (TLC), liquid
Packaging: 500mg
Price: $411
Updated: 2024/03/01

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(+/-)-NICOTINE Chemical Properties,Usage,Production

Chemical Properties

(+/-)-NICOTINE is Colourless Liquid

Uses

This is the unnatural isomer of Nicotine

Uses

(+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties.

Uses

Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tra ct and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.

Definition

ChEBI: 3-(1-methylpyrrolidin-2-yl)pyridine is an N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2. It is a N-alkylpyrrolidine, a pyridine alkaloid and a pyrrolidine alkaloid.

Biochem/physiol Actions

Prototype nicotinic acetylcholine receptor agonist.

Purification Methods

(+/-)-NICOTINE is purified by fractional distillation. Its solubility in EtOH is ~5%. The picrate forms yellow needles from hot H2O and has m 219o. The methiodide has m 219o (from MeOH). [Craig J Am Chem Soc 55 2854 1933, Nakane & Hutchinson J Org Chem 43 3922 1978, Beilstein 23/6 V 64.] POISONOUS.

(+/-)-NICOTINE Preparation Products And Raw materials

Raw materials

CALCIUM CARBONATE

Preparation Products

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(+/-)-NICOTINE Suppliers

Canada 3 China 68 Europe 2 France 1 Germany 1 India 6 Switzerland 1 United Kingdom 4 United States 11 Global 97

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
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Syntechem Co.,Ltd

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Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
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Clearsynth Labs Limited

Tel: +91-22-26355700
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TianJin Alta Scientific Co., Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Sigma-Aldrich

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Alta Scientific Co., Ltd.

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Chengdu jingzhihuacheng Chemical Technology Co., Ltd.

Tel: 028-37664989 15900794981
Email: jingzhichem@163.com
Country: China
ProdList: 894
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View Lastest Price from (+/-)-NICOTINE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: (±)-Nicotine 22083-74-5
Price: US $0.00/ml
Min. Order: 0.1ml
Purity: ≥98%(HPLC)
Supply Ability: 100 ml
Release date: 2020-05-25

22083-74-5, (+/-)-NICOTINERelated Search:

Nicotinic acid Nicotinamide NICOTINE BI-L-(+)-TARTRATE DL-Nicotine-d3 (methyl-d3),TRIDEUTEROMETHYL-NICOTINE,dl-nicotine-methyl-d3,nicotine-d3(methyl-d3) (-)-NICOTINE D-(+)-HYDROGEN TARTRATE (Nicotine Metabolite) Nicotine (+/-)-COTININE-D3 (+/-)-NICOTINE (-)-COTININE NICOTINE SALICYLATE Nicotine Sulfate (40-45% in Water as Nicotine base) (+)-NICOTINE-(+)-DI-P-TOLUOYL TARTRATE NICOTINE, L-, [N-METHYL-3H] rac trans-4-Cotininecarboxylic Acid NICOTINE, D [N-METHYL 14C] (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT NICOTINE, DL-, [N-METHYL-3H]

1-METHYL-2-(3-PYRIDYL)PYRROLIDINE

BLACK LEAF 40

(+/-)-NICOTINE

NICOTINE

(r,s)-nicotine

3-(1-methyl-2-pyrrolidinyl)-pyridin

3-(1-methyl-pyrrolidin-2-yl)-pyridine

rac-Nicotine

(±)-Nicotine-d7

(+-)-nicotin

(+-)-pyridin

(+)-3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine

(2R)-1-Methyl-2-(3-pyridyl)pyrrolidine

3-[(2R)-1-Methyl-2-pyrrolidinyl]pyridine

dl-beta-nicotine

dl-nicotine

(-)-1-Methyl-2-[3-pyridyl]pyrrolidine, free base

R-(+)-Nicotine, [+]-1-Methyl-2-[3-pyridyl]pyrrolidine, Free Base

NICOTINE ALKALOID 95%

NICOTINE ALKALOID USP

DL-Nicotine-d3 (N-methyl-d3)

Nicotine salts: (d1-beta-Nicotine: DL-Nicotine)

Nicotine for system suitability CRS

(+/-)-NICOTINE USP/EP/BP

(+/-)-NICOTINE

Acrylamide Impurity 19

22083-74-5

Ligand-Gated Ion Channels

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Nicotinic Acetylcholine Receptor Modulators

Ion Channels

AgonistsIon Channels

Cholinergics

Ligand-Gated Ion Channels

Neurotransmitters

Nicotinic Acetylcholine Receptor Modulators

Nicotine Derivatives

Neurochemicals