2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
- Product Name
- 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
- CAS No.
- 72648-12-5
- Chemical Name
- 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
- Synonyms
- AKOS BBS-00001893;2-CHLORO-3-TRICHLOROMETHYLPYRIDINE;Pyridine, 2-chloro-3-(trichloromethyl)-;2-CHLORO-3-TRICHLOROMETHYLPYRIDINE ISO 9001:2015 REACH;TIANFUCHEM-- 72648-12-5--High purity 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE in stock
- CBNumber
- CB9423596
- Molecular Formula
- C6H3Cl4N
- Formula Weight
- 230.91
- MOL File
- Mol file
2-CHLORO-3-TRICHLOROMETHYLPYRIDINE Property
- Boiling point:
- 291.5±35.0 °C(Predicted)
- Density
- 1.582±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -1.43±0.10(Predicted)
- InChI
- InChI=1S/C6H3Cl4N/c7-5-4(6(8,9)10)2-1-3-11-5/h1-3H
- InChIKey
- TZKVGCQBQQFWOV-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=CC=C1C(Cl)(Cl)Cl
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C386048
- Product name
- 2-Chloro-3-(trichloromethyl)pyridine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H32-5-KE
- Product name
- 2-Chloro-3-(trichloromethyl)pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $108
- Updated
- 2021/12/16
- Product number
- 3H32-5-KE
- Product name
- 2-Chloro-3-(trichloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5G
- Price
- $250
- Updated
- 2021/12/16
- Product number
- A271263
- Product name
- 2-Chloro-3-(trichloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $359
- Updated
- 2021/12/16
- Product number
- CM175847
- Product name
- 2-chloro-3-(trichloromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $421
- Updated
- 2021/12/16
2-CHLORO-3-TRICHLOROMETHYLPYRIDINE Chemical Properties,Usage,Production
Synthesis
609-71-2
72648-12-5
The general procedure for the synthesis of 2-chloro-3-trichloromethylpyridine from 2-hydroxynicotinic acid is as follows: a mixture of 2-hydroxypyridine-3-carboxylic acid (100.0 mmol), phenylphosphonic dichloride (33.0 mmol) and phosphorus pentachloride (330.0 mmol) was slowly heated to 160°C and distilled to remove the by-product phosphorus oxychloride (POCl3). Subsequently, the reaction mixture was stirred continuously at the same temperature for 5 hours. The completion of the reaction was confirmed by thin layer chromatography (TLC) monitoring. At the end of the reaction, the remaining phosphorous trichloride was removed by vacuum evaporation. The residue was carefully poured into ice water and neutralized with saturated aqueous sodium carbonate solution to pH neutral, followed by extraction with ethyl acetate. The organic phase was washed with deionized water, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography or purified by distillation.
References
[1] Synthetic Communications, 2016, vol. 46, # 19, p. 1619 - 1624
2-CHLORO-3-TRICHLOROMETHYLPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE manufacturers
- Product
- 2-Chloro-3-(trichloromethyl)pyridine 72648-12-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 250KG
- Purity
- Purity: 99%
- Supply Ability
- 1000tons
- Release date
- 2025-07-20
- Product
- 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE 72648-12-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-31
- Product
- 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE 72648-12-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000lkg
- Release date
- 2018-08-20