ChemicalBook > CAS DataBase List > EPA

EPA

Product Name
EPA
CAS No.
10417-94-4
Chemical Name
EPA
Synonyms
EICOSAPENTAENOIC ACID;CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;ICOSAPENT;TIMNODONIC ACID;Eicosapentaenoic;5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID;Eicosapentaenoic acid (EPA);5,8,11,14,17-EICOSAPENTAENOIC ACID;EPA;92-PGM
CBNumber
CB9426441
Molecular Formula
C20H30O2
Formula Weight
302.45
MOL File
10417-94-4.mol
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EPA Property

Melting point:
−54-−53 °C(lit.)
Boiling point:
439℃
Density 
0.943 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.4977(lit.)
Flash point:
93 °C
storage temp. 
-20°C
solubility 
Soluble in methanol
form 
liquid
pka
4.75±0.10(Predicted)
color 
Colorless to pale yellow
Sensitive 
Air & Light Sensitive
Merck 
14,3531
BRN 
1714433
Stability:
Stable for 1 year as supplied (unopened). After opening, EPA must be stored under inert gas at -80°C. Solutions in DMSO or ethanol should also be stored under inert gas and may be kept at -80°C for up to 2 months.
InChIKey
RRGOKSYVAZDNKR-ARJAWSKDSA-N
LogP
6.232 (est)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
F 
8-10-23
HazardClass 
8
HS Code 
29161900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
44864
Product name
cis-5,8,11,14,17-Eicosapentaenoic acid
Purity
analytical standard
Packaging
100mg
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
44864
Product name
cis-5,8,11,14,17-Eicosapentaenoic acid
Purity
analytical standard
Packaging
500mg
Price
$756
Updated
2024/03/01
Sigma-Aldrich
Product number
E-113
Product name
cis-5,8,11,14,17-Eicosapentaenoic acid
Purity
500?μg/mLinethanol,certifiedreferencematerial,Cerilliant?
Packaging
1mL
Price
$113
Updated
2022/05/15
TCI Chemical
Product number
E0441
Product name
all cis-5,8,11,14,17-Eicosapentaenoic Acid
Purity
>95.0%(GC)
Packaging
100mg
Price
$248
Updated
2024/03/01
TCI Chemical
Product number
E0441
Product name
all cis-5,8,11,14,17-Eicosapentaenoic Acid
Purity
>95.0%(GC)
Packaging
500mg
Price
$739
Updated
2024/03/01
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EPA Chemical Properties,Usage,Production

Description

EPA is an ω-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.

Chemical Properties

Colorless Oil

Uses

Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the “methyl end” of the molecule. Antilipemic.

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid has been used an analytical standard for the synthesis followed by investigation of pharmacological properties of aconitine-derived lipo-alkaloids.

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid has been used:

  • to test pharmacologic effect on steatosis in hepatocytes
  • as an analytical standard in Raman spectra measurements to characterize human breast cancer samples
  • in lipid peroxidation assay in mouse embryonic fibroblasts and in pre-treatment of cells for cell viability studies

Definition

ChEBI: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

brand name

Decabid (Lilly).

General Description

Eicosapentaenoic acid (cis-5,8,11,14,17), also known as EPA, is a long-chain omega-3 fatty acid. Studies suggests that EPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders. This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in mass spectrometry-based EPA testing applications such as assessment of cardiovascular?disease risk and fatty acid deficiency, and detection and quantification of EPA in nutraceuticals and dietary supplements.

Biochem/physiol Actions

5-Lipoxygenase inhibitor; reduces thromboxane A2 production.

References

1) Lee et al. (1985), Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function; N. Engl. J. Med., 312 1217 2) Nicholson et al. (2013), The role of marine n-3 fatty acids in improving cardiovascular health: a review; Food Funct., 4 357

EPA Preparation Products And Raw materials

Raw materials

unsaturated fatty acid Fatty acid ethyl ester FISH OIL Urea Light alkaline water Arachidonic acid

Preparation Products

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EPA Suppliers

Americas 1 Belgium 1 Canada 4 China 222 Europe 1 France 2 Germany 7 India 12 Japan 8 Poland 1 South Korea 1 Spain 1 Sweden 1 Switzerland 3 United Kingdom 10 United States 56 Global 331
Shanghai Tauto Biotech Co., Ltd.
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Shaanxi Pioneer Biotech Co., Ltd
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029-86621125 18123784671
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J & K SCIENTIFIC LTD.
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Energy Chemical
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View Lastest Price from EPA manufacturers

airuikechemical co., ltd.
Product
Eicosapentaenoic Acid 10417-94-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-07
Nantong Guangyuan Chemicl Co,Ltd
Product
Eicosapentaenoic Acid 10417-94-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-12-05
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Eicosapentaenoic acid EPA 10417-94-4 10417-94-4
Price
US $20.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-19

10417-94-4, EPARelated Search:

Docosahexaenoic Acid DOCOSAHEXAENOIC ACID METHYL ESTER CIS-4,7,10,13,16,19-DOCOSAHEXAENOIC ACID METHYL ESTER CIS-4,7,10,13,16,19-DOCOSAHEXAENOIC ACID ETHYL ESTER 5(Z),8(Z),11(Z),14(Z),17(Z),20(Z)-TRICOSAHEXAENOIC ACID CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID METHYL ESTER EPA EPA Cholesteryl Eicosapentaenoate ALL CIS 5-8-11-14-17 EPA ETHYL ESTER,ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER,CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER EPA 1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE eicosapentaenoic acid ethyl ester 12S-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID [5S,12R]-DIHYDROXY-[6Z,8E,10E,14Z,17Z]-EICOSAPENTAENOIC ACID (+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID,5-hydroxy-6,8,11,14,17-eicosapentaenoic acid,5-hydroxy-6,8,11,14,17-eicosapentaenoic acid 11R-HYDROXY-5Z,8Z,12E,14Z,17Z-EICOSAPENTAENOIC ACID Eicosapentaenoic Acid-d5

  • TIMNODONIC ACID
  • TIMNODONIC ACID(EPA)
  • C20:5 (ALL CIS-5,8,11,14,17) ACID
  • C20:5 OMEGA-3
  • CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
  • EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID
  • EICOSAPENTAENOIC CID
  • EICOSAPENTAENOIC ACID
  • EPA
  • EPA 5C,8C,11C,14C,17C
  • ICOSAPENT
  • 5,8,11,14,17-EICOSAPENTAENOIC ACID
  • 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
  • 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID
  • ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
  • ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID
  • ALL CIS 5-8-11-14-17 EPA
  • (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid
  • CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*F REE ACID AP
  • 5,8,11,14,17-EICOSAPENTAENOIC ACID, STAN DARD FOR GC
  • CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID, 90+%
  • Eicosapentaenoic
  • 5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)-
  • (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid
  • eiosapentaenoic acid，EPA
  • 5,8,11,14,
  • acid 5,
  • EPA / DHA 40%
  • EPA 18 / DHA 12
  • EPA 18 / DHA 12 DEODORIZED
  • SEA OIL POWDER 30 EPA 18 / DHA 12
  • Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)
  • Single-Use Eicosapentaenoic Acid (peroxide free)
  • CIS-5,8,11,14,17-EICOSAPENTAENOIC AC
  • cis-4,7,10,13,16,19-Docosapentaenoic Solution, 100ppm
  • Eicosapentaenoic acid EPA 10417-94-4
  • cis-5,8,11,14,17-Eicosapentaenoic Acid(Epa-M)(C20:5)
  • Eicosapentaenoic Acid Powder
  • (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid
  • EPA 45G
  • Icosapentaenoic Acid
  • Incromega E 7010SR
  • Ropufa 70
  • 5，8，11，14，17-eicosapentaenoic acid: EPA
  • (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Icosapentaenoic acid
  • 92-PGM
  • 5,8,11,14,17-Eicosapentaenoic acid (all-cis)
  • EICOSAPENTAENOIC ACID(EPA)(SG)
  • cis-5,8,11,14,17-Eicosapentaenoic acid ,95%
  • cis-5,8,11,14,17-Eicosapentaenoic acid ,70%
  • cis-5,8,11,14,17-Eicosapentaenoic acid,EPA, Timnodonic acid
  • Eicosapentaenoic Acid (peroxide free)
  • EPA (Eicosapentaenoic Acid)
  • EPA, Timnodonic acid
  • EPA all cis-5,8,11,14,17-Icosapentaenoic Acid
  • Eicosapentaenoic acid (EPA)
  • Eicosapentaenoic acid (EPA) -d5
  • cis-5,8,11,14,17-Dicosapentaenoic acid