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DL-NORPHENYLEPHRINE HYDROCHLORIDE

Product Name
DL-NORPHENYLEPHRINE HYDROCHLORIDE
CAS No.
4779-94-6
Chemical Name
DL-NORPHENYLEPHRINE HYDROCHLORIDE
Synonyms
WV 569;Coritat;Vingsal;Energona;Esbuphon;Stagural;Tonolift;Molycor R;NSC 100733;NSC 297582
CBNumber
CB9429008
Molecular Formula
C8H12ClNO2
Formula Weight
189.64
MOL File
4779-94-6.mol
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DL-NORPHENYLEPHRINE HYDROCHLORIDE Property

Melting point:
162-164 °C(lit.)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Merck 
14,6699
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
DN7400000
HS Code 
2922504500
Toxicity
LD50 oral in rat: 390mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1473206
Product name
Norphenylephrine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1490
Updated
2024/03/01
Sigma-Aldrich
Product number
113727
Product name
Norphenylephrine hydrochloride
Purity
98%
Packaging
10g
Price
$135
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1536
Product name
Norphenylephrine Hydrochloride
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
200mg
Price
$315
Updated
2024/03/01
TRC
Product number
N825500
Product name
racNorphenylephrineHydrochloride(PhenylephrineImpurityA)
Packaging
250mg
Price
$425
Updated
2021/12/16
Biosynth Carbosynth
Product number
IN27563
Product name
rac-Norphenylephrine hydrochloride
Packaging
100g
Price
$500
Updated
2021/12/16
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DL-NORPHENYLEPHRINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Originator

Zordel,Grelan,Japan,1970

Uses

rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.

Definition

ChEBI: Norfenefrine hydrochloride is a member of phenols.

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

DL-NORPHENYLEPHRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-NORPHENYLEPHRINE HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4969
Advantage
50
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from DL-NORPHENYLEPHRINE HYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
DL-NORPHENYLEPHRINE HYDROCHLORIDE 4779-94-6
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-11
Dideu Industries Group Limited
Product
DL-NORPHENYLEPHRINE HYDROCHLORIDE 4779-94-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-11

4779-94-6, DL-NORPHENYLEPHRINE HYDROCHLORIDERelated Search:


  • alpha-(aminomethyl)-3-hydroxy-benzenemethanohydrochloride
  • alpha-aminomethyl-3-hydroxy-benzylalcohohydrochloride
  • m-octopaminehydrochloride
  • norfenefrin
  • Phenylephrine Hydrochloride Impurity A
  • α-(AMinoMethyl)-3-hydroxybenzeneMethanol
  • 3-(2-aMino-1-hydroxyethyl)phenol hydrochloride
  • Phenylephrine Impurity A HCl (racemic Norphenylephrine HCl)
  • Phenylephrine, Neosynephrine, Neophyrin, Mesaton
  • 3-(2-amino-1-hydroxyethyl)phenol:hydron:chloride
  • Phenylephrine Impurity 16(Racemic Phenylephrine EP Impurity A HCl)
  • Phenylephrine Impurity A HCl
  • rac-Norphenylephrine hydrochloride
  • Racemic Phenylephrine EP Impurity A HCl
  • (+/-)-NORPHENYLEPHRINE HYDROCHLORIDE, 98 %
  • α-aminomethyl-3-hydroxybenzyl alcohol hydrochloride
  • 1-(m-Hydroxyphenyl)-2-aminoethanol hydrochloride
  • 2-Amino-1-(3-hydroxyphenyl)ethanol hydrochloride
  • Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride (9CI)
  • Benzyl alcohol, a-(aminomethyl)-m-hydroxy-, hydrochloride (6CI, 8CI)
  • Coritat
  • Depot-Novadral
  • dl-Norfenefrine hydrochloride
  • Energona
  • Esbuphon
  • Molycor R
  • nofenefrine hydrochloride
  • NSC 100733
  • NSC 297582
  • Stagural
  • Tonolift
  • Vingsal
  • WV 569
  • α-Aminomethyl-4-hydroxybenzyl alcohol hydrochloride
  • norphenephrinehydrochloride
  • A-AMINOMETHYL-M-HYDROXYBENZYLALCOHOL HYDROCHLORIDE
  • (+/-)-NORPHENYLEPHRINE HYDROCHLORIDE
  • NORPHENYLEPHRINE HYDROCHLORIDE
  • M-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE
  • TIMTEC-BB SBB000279
  • rac Norphenylephrine Hydrochloride (Phenylephrine Impurity A)
  • rac-Phenylephrine EP Impurity A HCl
  • Phenylephrine Impurity A
  • Phenylephrine EP Impurity A Racemate
  • Etilefrine EP Impurity C
  • Octopamine Impurity 12
  • Benzenemethanol, a-(aminomethyl)-3-hydroxy-,hydrochloride (1:1)
  • DL-NORPHENYLEPHRINE HYDROCHLORIDE USP/EP/BP
  • Noradrenaline (Norepinephrine) Impurity 51
  • (RS)-NORPHENYLEPHRINE HYDROCHLORIDE
  • racemic Norphenylephrine HCl
  • Norphenylephrine Hydrochloride (1473206)
  • Phenylephrine EP Impurity A Racemate HCl
  • Phenylephrine Hydrochloride Impurity A as Racemate Hydrochloride
  • Etilefrine Hydrochloride Impurity C as Hydrochloride
  • Phenylephrine Hydrochloride EP Impurity A as Racemate Hydrochloride
  • Rac-Phenylephrine EP Impurity A HCl(Etilefrine EP Impurity C HCl)
  • Etilefrine Hydrochloride EP Impurity C as Hydrochloride