DL-NORPHENYLEPHRINE HYDROCHLORIDE

ChemicalBook > CAS DataBase List > DL-NORPHENYLEPHRINE HYDROCHLORIDE

DL-NORPHENYLEPHRINE HYDROCHLORIDE

Product Name: DL-NORPHENYLEPHRINE HYDROCHLORIDE
CAS No.: 4779-94-6
Chemical Name: DL-NORPHENYLEPHRINE HYDROCHLORIDE
Synonyms: WV 569;Coritat;Vingsal;Energona;Esbuphon;Stagural;Tonolift;Molycor R;NSC 100733;NSC 297582
CBNumber: CB9429008
Molecular Formula: C8H11NO2.ClH
Formula Weight: 189.64
MOL File: 4779-94-6.mol

Less

DL-NORPHENYLEPHRINE HYDROCHLORIDE Property

Melting point:: 162-164 °C(lit.)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Merck: 14,6699

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: DN7400000
HS Code: 2922504500
Toxicity: LD50 oral in rat: 390mg/kg

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1473206
Product name: Norphenylephrine hydrochloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1490
Updated: 2024/03/01

Sigma-Aldrich

Product number: 113727
Product name: Norphenylephrine hydrochloride
Purity: 98%
Packaging: 10g
Price: $135
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR1536
Product name: Norphenylephrine Hydrochloride
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 200mg
Price: $315
Updated: 2024/03/01

TRC

Product number: N825500
Product name: racNorphenylephrineHydrochloride(PhenylephrineImpurityA)
Packaging: 250mg
Price: $425
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IN27563
Product name: rac-Norphenylephrine hydrochloride
Packaging: 100g
Price: $500
Updated: 2021/12/16

Less

DL-NORPHENYLEPHRINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Originator

Zordel,Grelan,Japan,1970

Uses

rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.

Definition

ChEBI: Norfenefrine hydrochloride is a member of phenols.

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

DL-NORPHENYLEPHRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

DL-NORPHENYLEPHRINE HYDROCHLORIDE Suppliers

Americas 1 Canada 1 China 64 Europe 2 Germany 2 India 9 Japan 1 Switzerland 1 United Kingdom 5 United States 12 Global 98

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5047
Advantage: 50

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 2024
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

klamar reagent

Tel: 4001650900
Fax: 021-64897811
Email: sales-wang@klamar-reagent.com
Country: China
ProdList: 1986
Advantage: 55

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 1963319514@qq.com
Country: China
ProdList: 14224
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 18016230971
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 24969
Advantage: 58

Shanghai Benso Pharmaceutical Technology Co., Ltd.

Tel: 15088289376
Email: 248775804@qq.com
Country: China
ProdList: 4983
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 0755-22202135 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 8897
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7774
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34553
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
Advantage: 58

Shenzhen ruikai de biotechnology co., ltd.

Tel: 0755-61348847 17820674378
Fax: 0755-21016893
Email: 2682116078@qq.com
Country: China
ProdList: 7843
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10005
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: info@synzest.com
Country: China
ProdList: 9286
Advantage: 58

Shanghai Sunmonth Technology Co., LTD

Tel: 15216675652
Email: xuanyuelj@163.com
Country: China
ProdList: 2568
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Shanghai kadel chemical technology co., LTD

Tel: 021-4007787-550 400-7787-550
Email: 2850202386@qq.com
Country: China
ProdList: 10594
Advantage: 58

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 9996
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 027-81302411 15377658509
Email: zs@dkybpc.com
Country: China
ProdList: 2196
Advantage: 58

Molcoo Chemicals Inc.

Tel: 18627756402
Email: 3001051413@qq.com
Country: China
ProdList: 9544
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 18351873721
Email: helen.zhang@synzest.com
Country: China
ProdList: 8295
Advantage: 58

PureChemland Co.,Ltd.

Tel: 18581895003 18084815636
Email: 3848291069@qq.com
Country: China
ProdList: 3594
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002
Email: zhejia01@163.com
Country: China
ProdList: 8870
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9951
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24647
Advantage: 58

Scinova Biotech(Guangzhou) Co., Ltd.

Tel: 13268215580
Email: scinova_sales@163.com
Country: China
ProdList: 7023
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175-877 18933936954
Email: tianwen.zhan@cato-chem.com
Country: China
ProdList: 7735
Advantage: 58

Shanghai klamar Reagent Co., LTD

Tel: 4001650900 13817534909
Email: 3003940895@qq.com
Country: China
ProdList: 10720
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 15583
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

HX Pharmaceutical technology co., LTD

Tel: 15671363360
Email: 494267389@qq.com
Country: China
ProdList: 3220
Advantage: 58

Shanghai Saikerui Biotechnology Co. , Ltd.

Tel: 021-58000709 15900491054
Email: info@scrbio.com
Country: China
ProdList: 10329
Advantage: 58

Shenzhen Excellent Biomedical Technology Co., Ltd.

Tel: 18318671572
Email: 2850803126@qq.com
Country: China
ProdList: 4986
Advantage: 58

Hebei duofang Technology Co. , Ltd.

Tel: 13127301785 13127301785
Email: 1720153048@qq.com
Country: China
ProdList: 447
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 17691182729 15529505138
Email: 1021@dideu.com
Country: China
ProdList: 9969
Advantage: 58

Shanghai Zerui Biotechnology Co., Ltd.

Tel: 021-54580889 18321124657
Fax: 021-54580889
Email: 731997554@qq.com
Country: China
ProdList: 10608
Advantage: 58

Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd

Tel: 18502726233; 18502726233
Email: 3641133981@qq.com
Country: China
ProdList: 9705
Advantage: 58

4779-94-6, DL-NORPHENYLEPHRINE HYDROCHLORIDERelated Search:

Phenylephrine hydrochloride 1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline Phenylephrine EP Impurity D Phenylephrine EP Impurity D 3-Hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]MethylaMino]-4-oxo-butanoic Acid 1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline N-ACETYL-4-BENZOQUINONE IMINE Phenylephrine Impurity 32 N-(2-Succinyl) Phenylephrine 2,2-Dichloro-1-(3-hydroxyphenyl)-ethanone benzyl(3-hydroxyphenacyl)methylammonium chloride N-Acetylphenylephrine DL-NORPHENYLEPHRINE HYDROCHLORIDE 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (R)-(-)-Phenylephrine-d3 HCl 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Phenylephrine Impurity 33 rac Benzyl Phenylephrine Norphenylephrine Hydrochloride

alpha-(aminomethyl)-3-hydroxy-benzenemethanohydrochloride

alpha-aminomethyl-3-hydroxy-benzylalcohohydrochloride

m-octopaminehydrochloride

norfenefrin

Phenylephrine Hydrochloride Impurity A

α-(AMinoMethyl)-3-hydroxybenzeneMethanol

3-(2-aMino-1-hydroxyethyl)phenol hydrochloride

Phenylephrine Impurity A HCl (racemic Norphenylephrine HCl)

Phenylephrine, Neosynephrine, Neophyrin, Mesaton

3-(2-amino-1-hydroxyethyl)phenol:hydron:chloride

Phenylephrine Impurity 16(Racemic Phenylephrine EP Impurity A HCl)

Phenylephrine Impurity A HCl

rac-Norphenylephrine hydrochloride

Racemic Phenylephrine EP Impurity A HCl

(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE, 98 %

α-aminomethyl-3-hydroxybenzyl alcohol hydrochloride

1-(m-Hydroxyphenyl)-2-aminoethanol hydrochloride

2-Amino-1-(3-hydroxyphenyl)ethanol hydrochloride

Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride (9CI)

Benzyl alcohol, a-(aminomethyl)-m-hydroxy-, hydrochloride (6CI, 8CI)

Coritat

Depot-Novadral

dl-Norfenefrine hydrochloride

Energona

Esbuphon

Molycor R

nofenefrine hydrochloride

NSC 100733

NSC 297582

Stagural

Tonolift

Vingsal

WV 569

α-Aminomethyl-4-hydroxybenzyl alcohol hydrochloride

norphenephrinehydrochloride

A-AMINOMETHYL-M-HYDROXYBENZYLALCOHOL HYDROCHLORIDE

(+/-)-NORPHENYLEPHRINE HYDROCHLORIDE

NORPHENYLEPHRINE HYDROCHLORIDE

M-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE

TIMTEC-BB SBB000279

rac Norphenylephrine Hydrochloride (Phenylephrine Impurity A)

rac-Phenylephrine EP Impurity A HCl

Phenylephrine Impurity A

Phenylephrine EP Impurity A Racemate

Etilefrine EP Impurity C

Octopamine Impurity 12

Benzenemethanol, a-(aminomethyl)-3-hydroxy-,hydrochloride (1:1)

DL-NORPHENYLEPHRINE HYDROCHLORIDE USP/EP/BP

Noradrenaline (Norepinephrine) Impurity 51

(RS)-NORPHENYLEPHRINE HYDROCHLORIDE

racemic Norphenylephrine HCl

Norphenylephrine Hydrochloride (1473206)

Phenylephrine EP Impurity A Racemate HCl

Phenylephrine Hydrochloride Impurity A as Racemate Hydrochloride

Etilefrine Hydrochloride Impurity C as Hydrochloride

Phenylephrine Hydrochloride EP Impurity A as Racemate Hydrochloride

Rac-Phenylephrine EP Impurity A HCl(Etilefrine EP Impurity C HCl)

Etilefrine Hydrochloride EP Impurity C as Hydrochloride