ChemicalBook > CAS DataBase List > METHYLSULFONYLACETONITRILE

METHYLSULFONYLACETONITRILE

Product Name: METHYLSULFONYLACETONITRILE
CAS No.: 2274-42-2
Chemical Name: METHYLSULFONYLACETONITRILE
Synonyms: NSC 207832;CHEBI:32444;mesylacetonitrile;2-mesylacetonitrile;Methylsufonylacetonitrile;CYANOMETHYLSULFONYLMETHANE;METHYLSULFONYLACETONITRILE;Cyanomethyl methyl sulphone;Methylsulphonylacetonitrile;METHANESULFONYLACETONITRILE
CBNumber: CB9435816
Molecular Formula: C3H5NO2S
Formula Weight: 119.14
MOL File: 2274-42-2.mol

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METHYLSULFONYLACETONITRILE Property

Melting point:: 81-84 °C(lit.)
Boiling point:: 360.6±25.0 °C(Predicted)
Density: 1.288±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Powder or Crystalline Powder
color: White to off-white
Water Solubility: Slightly soluble in water.
BRN: 969929
InChI: InChI=1S/C3H5NO2S/c1-7(5,6)3-2-4/h3H2,1H3
InChIKey: FOTRKCAZUSJCQD-UHFFFAOYSA-N
SMILES: C(#N)CS(C)(=O)=O
CAS DataBase Reference: 2274-42-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,T
Risk Statements: 20/21/22
Safety Statements: 22-26-36
RIDADR: UN 3439 6.1/PG 3
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 184365
Product name: (Methylsulfonyl)acetonitrile
Purity: 97%
Packaging: 25g
Price: $274.55
Updated: 2025/07/31

TCI Chemical

Product number: M0667
Product name: Methylsulfonylacetonitrile
Purity: >98.0%(GC)
Packaging: 5g
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: M0667
Product name: Methylsulfonylacetonitrile
Purity: >98.0%(GC)
Packaging: 25g
Price: $198
Updated: 2025/07/31

TRC

Product number: M218898
Product name: Methylsulfonylacetonitrile
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 086104
Product name: (Methylsulfonyl)acetonitrile
Purity: 97%
Packaging: 1g
Price: $56
Updated: 2021/12/16

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METHYLSULFONYLACETONITRILE Chemical Properties,Usage,Production

Uses

Methylsulfonylacetonitrile is used in preparation of substituted pyrimidinylamino isoquinoline and naphthyridine compounds as inhibitors of mutant forms of EGFR.

Uses

(Methylsulfonyl)acetonitrile was used in the synthesis of:

substituted δ-pyrone ring analogues
4,9-dihydropyrrolo[2,1-b]quinazolines containing electron withdrawing groups at the 3-position

Definition

ChEBI: (methylsulfonyl)acetonitrile is an aliphatic nitrile.

METHYLSULFONYLACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from METHYLSULFONYLACETONITRILE manufacturers

Career Henan Chemical Co

Product: METHYLSULFONYLACETONITRILE 2274-42-2
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

2274-42-2, METHYLSULFONYLACETONITRILERelated Search:

4-CHLOROPHENYLSULFONYLACETONITRILE METHYLSULFONYLACETONITRILE N-HEXANESULFONYLACETONITRILE 2-PYRIDINESULFONYLACETONITRILE 4-(Methylphenyl)sulfonylacetonitrile THIOPHENE-2-SULFONYLACETONITRILE SULPHONYLDIACETONITRILE (PHENYLSULFONYL)ACETONITRILE Acetonitrile 2-(TERT-BUTYLSULFONYL)-3-ETHOXYACRYLONITRILE 2-[(4-CHLOROBENZYL)SULFONYL]ACETONITRILE 3-ETHOXY-2-(ISOPROPYLSULFONYL)ACRYLONITRILE 2-(2-NAPHTHYLSULFONYL)ACETONITRILE 3-ETHOXY-2-(2-NAPHTHYLSULFONYL)ACRYLONITRILE 2-(TERT-BUTYLSULFONYL)ACETONITRILE 3-ETHOXY-2-(PROPYLSULFONYL)ACRYLONITRILE 1-PROPANESULPHONYLACETONITRILE 2-PROPANESULPHONYLACETONITRILE

2-(METHYLSULFONYL)ACETONITRILE

Methylsulphonylacetonitrile

mesylacetonitrile

2-(Methylsulphonyl)acetonitrile

Methanesulfonylacetonitrile,98+%

Methanesulphonylacetonitrile,98+%

Methylsulfonylacetonitrile, 98+%

Methylsufonylacetonitrile

Cyanomethyl methyl sulphone

Cyanomethylsulfonylmethane Methanesulfonylacetonitrile

Cyanomethyl methyl sulphone, 2-(Methylsulphonyl)ethanonitrile

2-Methanesulfonylacetonitrile

2-mesylacetonitrile

2-methylsulfonylethanenitrile

CHEBI:32444

NSC 207832

METHANESULPHONYLACETONITRILE

METHANESULFONYLACETONITRILE

Acetonitrile, (methylsulfonyl)-

CYANOMETHYLSULFONYLMETHANE

METHYLSULFONYLACETONITRILE

Methylsulfonylacetonitrile&gt

Acetonitrile, 2-(methylsulfonyl)-

2274-42-2

2274-42-4

C3H5NO2S

3H5NO2S

CH3SO2CH2CN

Building Blocks

C1 to C5

Organic Building Blocks

Nitrogen Compounds

Cyanides/Nitriles

Aliphatics

C1 to C5

Cyanides/Nitriles

Nitrogen Compounds