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METHYLSULFONYLACETONITRILE

Product Name
METHYLSULFONYLACETONITRILE
CAS No.
2274-42-2
Chemical Name
METHYLSULFONYLACETONITRILE
Synonyms
NSC 207832;CHEBI:32444;mesylacetonitrile;2-mesylacetonitrile;Methylsufonylacetonitrile;CYANOMETHYLSULFONYLMETHANE;METHYLSULFONYLACETONITRILE;Cyanomethyl methyl sulphone;Methylsulphonylacetonitrile;METHANESULFONYLACETONITRILE
CBNumber
CB9435816
Molecular Formula
C3H5NO2S
Formula Weight
119.14
MOL File
2274-42-2.mol
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METHYLSULFONYLACETONITRILE Property

Melting point:
81-84 °C(lit.)
Boiling point:
360.6±25.0 °C(Predicted)
Density 
1.288±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Powder or Crystalline Powder
color 
White to off-white
Water Solubility 
Slightly soluble in water.
BRN 
969929
CAS DataBase Reference
2274-42-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
20/21/22
Safety Statements 
22-26-36
RIDADR 
UN 3439 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
184365
Product name
(Methylsulfonyl)acetonitrile
Purity
97%
Packaging
25g
Price
$112
Updated
2024/03/01
TCI Chemical
Product number
M0667
Product name
Methylsulfonylacetonitrile
Purity
>98.0%(GC)
Packaging
5g
Price
$67
Updated
2024/03/01
TCI Chemical
Product number
M0667
Product name
Methylsulfonylacetonitrile
Purity
>98.0%(GC)
Packaging
25g
Price
$201
Updated
2024/03/01
Alfa Aesar
Product number
L03280
Product name
Methylsulfonylacetonitrile, 98+%
Packaging
10g
Price
$117.65
Updated
2024/03/01
Alfa Aesar
Product number
L03280
Product name
Methylsulfonylacetonitrile, 98+%
Packaging
50g
Price
$444.65
Updated
2024/03/01
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METHYLSULFONYLACETONITRILE Chemical Properties,Usage,Production

Uses

Methylsulfonylacetonitrile is used in preparation of substituted pyrimidinylamino isoquinoline and naphthyridine compounds as inhibitors of mutant forms of EGFR.

Uses

(Methylsulfonyl)acetonitrile was used in the synthesis of:

  • substituted δ-pyrone ring analogues
  • 4,9-dihydropyrrolo[2,1-b]quinazolines containing electron withdrawing groups at the 3-position

Definition

ChEBI: (methylsulfonyl)acetonitrile is an aliphatic nitrile.

METHYLSULFONYLACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYLSULFONYLACETONITRILE Suppliers

Americas 1 Belgium 1 China 81 Europe 1 Germany 4 India 2 Japan 1 Switzerland 1 United Kingdom 11 United States 20 Global 123
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from METHYLSULFONYLACETONITRILE manufacturers

Career Henan Chemical Co
Product
METHYLSULFONYLACETONITRILE 2274-42-2
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

2274-42-2, METHYLSULFONYLACETONITRILERelated Search:

4-CHLOROPHENYLSULFONYLACETONITRILE METHYLSULFONYLACETONITRILE N-HEXANESULFONYLACETONITRILE 2-PYRIDINESULFONYLACETONITRILE 4-(Methylphenyl)sulfonylacetonitrile THIOPHENE-2-SULFONYLACETONITRILE SULPHONYLDIACETONITRILE (PHENYLSULFONYL)ACETONITRILE Acetonitrile 2-(TERT-BUTYLSULFONYL)-3-ETHOXYACRYLONITRILE 2-[(4-CHLOROBENZYL)SULFONYL]ACETONITRILE 3-ETHOXY-2-(ISOPROPYLSULFONYL)ACRYLONITRILE 2-(2-NAPHTHYLSULFONYL)ACETONITRILE 3-ETHOXY-2-(2-NAPHTHYLSULFONYL)ACRYLONITRILE 2-(TERT-BUTYLSULFONYL)ACETONITRILE 3-ETHOXY-2-(PROPYLSULFONYL)ACRYLONITRILE 1-PROPANESULPHONYLACETONITRILE 2-PROPANESULPHONYLACETONITRILE

  • 2-(METHYLSULFONYL)ACETONITRILE
  • Methylsulphonylacetonitrile
  • mesylacetonitrile
  • 2-(Methylsulphonyl)acetonitrile
  • Methanesulfonylacetonitrile,98+%
  • Methanesulphonylacetonitrile,98+%
  • Methylsulfonylacetonitrile, 98+%
  • Methylsufonylacetonitrile
  • Cyanomethyl methyl sulphone
  • Cyanomethylsulfonylmethane Methanesulfonylacetonitrile
  • Cyanomethyl methyl sulphone, 2-(Methylsulphonyl)ethanonitrile
  • 2-Methanesulfonylacetonitrile
  • 2-mesylacetonitrile
  • 2-methylsulfonylethanenitrile
  • CHEBI:32444
  • NSC 207832
  • METHANESULPHONYLACETONITRILE
  • METHANESULFONYLACETONITRILE
  • Acetonitrile, (methylsulfonyl)-
  • CYANOMETHYLSULFONYLMETHANE
  • METHYLSULFONYLACETONITRILE
  • Methylsulfonylacetonitrile&gt
  • Acetonitrile, 2-(methylsulfonyl)-
  • 2274-42-2
  • 2274-42-4
  • C3H5NO2S
  • 3H5NO2S
  • CH3SO2CH2CN
  • Building Blocks
  • C1 to C5
  • Organic Building Blocks
  • Nitrogen Compounds
  • Cyanides/Nitriles
  • Aliphatics
  • C1 to C5
  • Cyanides/Nitriles
  • Nitrogen Compounds