ALPHA-APO-OXYTETRACYCLINE
- Product Name
- ALPHA-APO-OXYTETRACYCLINE
- CAS No.
- 18751-99-0
- Chemical Name
- ALPHA-APO-OXYTETRACYCLINE
- Synonyms
- β-Apooxytetracycline;b-Apo-oxytetracycline;β-Apo-oxytetracycline;BETA-APO-OXYTETRACYCLINE;Apooxytetracycline, beta-;ALPHA-APO-OXYTETRACYCLINE;Oxytetracycline Impurity E;β-Apo-oxytetracycline, >85%;Oxytetracycline EP Impurity E;β-Apo-oxytetracycline, EvoPure?
- CBNumber
- CB9455892
- Molecular Formula
- C22H22N2O8
- Formula Weight
- 442.42
- MOL File
- 18751-99-0.mol
ALPHA-APO-OXYTETRACYCLINE Property
- Melting point:
- 200-204 °C
- Boiling point:
- 742.4±60.0 °C(Predicted)
- Density
- 1.62±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- solubility
- Aqueous Base (Slightly), Methanol (Slightly, Heated, Sonicated)
- form
- Powder
- pka
- 1.62±0.58(Predicted)
- color
- Yellow-brown to brown
- Stability:
- Unstable in basic solution
- EPA Substance Registry System
- 1-Cyclohexene-1-carboxamide, 4-(1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho[2,3-c]furan-1-yl)-3-(dimethylamino)-2,5-dihydroxy-6-oxo- (18751-99-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27099
- Product name
- β-Apooxytetracycline
- Packaging
- 1mg
- Price
- $76
- Updated
- 2024/03/01
- Product number
- 27099
- Product name
- β-Apooxytetracycline
- Packaging
- 10mg
- Price
- $583
- Updated
- 2024/03/01
- Product number
- 27099
- Product name
- β-Apooxytetracycline
- Packaging
- 500μg
- Price
- $40
- Updated
- 2024/03/01
- Product number
- 27099
- Product name
- β-Apooxytetracycline
- Packaging
- 5mg
- Price
- $312
- Updated
- 2024/03/01
- Product number
- 002804
- Product name
- β-Apo-oxytetracycline
- Packaging
- 1mg
- Price
- $340
- Updated
- 2021/12/16
ALPHA-APO-OXYTETRACYCLINE Chemical Properties,Usage,Production
Description
β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. β-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli. β-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.
Chemical Properties
yellow-brown to brown powder
Uses
Oxytetracycline metabolite (absolute stereochemistry unknown)
Uses
β-Apooxytetracycline is a degradation product of oxytetracycline formed under acidic conditions. An initial dehydration to anhydrooxytetracycline then undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. β-apooxytetracycline is an important standard for monitoring oxytetracycline stability.
Uses
β-Apooxytetracycline is a degradation product of oxytetracycline formed under acidic conditions. After initial dehydration to anhydrooxytetracycline, it undergoes an internal cyclisation of the C5-OH to the C12 ketone. The resulting cleavage of the C12-C12a bond generates two isomers, α- and β-apooxytetracycline. β-Apooxytetracycline is an important standard for monitoring oxytetracycline stability.
ALPHA-APO-OXYTETRACYCLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ALPHA-APO-OXYTETRACYCLINE manufacturers
- Product
- ALPHA-APO-OXYTETRACYCLINE 18751-99-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-28
- Product
- ALPHA-APO-OXYTETRACYCLINE 18751-99-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25