5-Bromo-2-methylaniline
- Product Name
- 5-Bromo-2-methylaniline
- CAS No.
- 39478-78-9
- Chemical Name
- 5-Bromo-2-methylaniline
- Synonyms
- 5-Bromo-2-Methyl;2-AMINO-4-BROMOTOLUENE;5-Bromo-2-methylbenzenamine;5-BROMO-O-TOLUIDINE;3-Bromo-6-methylaniline;2-Methyl-5-bromoaniline;5-BROMO-2-METHYLANILINE;2-Methyl-5-Bromoaniline99%;5-Bromo-2-methylphenylamine;5-Bromo-2-methylaniline,98%
- CBNumber
- CB9461675
- Molecular Formula
- C7H8BrN
- Formula Weight
- 186.05
- MOL File
- 39478-78-9.mol
5-Bromo-2-methylaniline Property
- Melting point:
- 33 °C(lit.)
- Boiling point:
- 139 °C17 mm Hg(lit.)
- Density
- 1.49 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.614(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Liquid After Melting
- pka
- 3.38±0.10(Predicted)
- color
- Clear yellow to brown
- CAS DataBase Reference
- 39478-78-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- Hazard Note
- Harmful/Irritant
- HS Code
- 29214300
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 515019
- Product name
- 5-Bromo-2-methylaniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $67.1
- Updated
- 2023/06/20
- Product number
- 515019
- Product name
- 5-Bromo-2-methylaniline
- Purity
- 97%
- Packaging
- 25g
- Price
- $268
- Updated
- 2023/06/20
- Product number
- B3687
- Product name
- 5-Bromo-2-methylaniline
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- B3687
- Product name
- 5-Bromo-2-methylaniline
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $116
- Updated
- 2025/07/31
- Product number
- B808093
- Product name
- 5-Bromo-2-methylaniline
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
5-Bromo-2-methylaniline Chemical Properties,Usage,Production
Chemical Properties
clear yellow to brown liquid after melting
Uses
In industrial applications, 5-bromo-2-methylaniline is often used as a chemical intermediate for the synthesis of drugs, dyes or other chemicals.
Synthesis
60956-26-5
39478-78-9
The general procedure for the synthesis of 2-amino-4-bromotoluene from 4-bromo-2-nitrotoluene was as follows: first, 4-bromo-1-methyl-2-nitrobenzene (5 g, 23.14 mmol, 1.00 eq.), ethyl acetate (100 mL), and SnCl2-H2O (20 g) were added to a 250 mL round-bottom flask. The reaction mixture was stirred at 30 °C overnight. Upon completion of the reaction, the pH of the reaction solution was adjusted to 10 with 5 mol/L sodium hydroxide solution.Subsequently, the reaction solution was extracted with ethyl acetate (3 x 30 mL) and the organic layers were combined. The organic phase was sequentially washed with brine (3 × 50 mL), dried over anhydrous sodium sulfate and finally concentrated under reduced pressure. After the above steps, 4 g (93% yield) of 5-bromo-2-methylaniline was obtained as a brown oily product.
References
[1] Organic and Biomolecular Chemistry, 2013, vol. 11, # 19, p. 3116 - 3127
[2] Patent: US2015/366198, 2015, A1. Location in patent: Paragraph 0132
[3] Journal of Medicinal Chemistry, 2004, vol. 47, # 26, p. 6603 - 6608
[4] Patent: WO2003/99824, 2003, A1. Location in patent: Page 23
[5] Patent: US6337351, 2002, B1. Location in patent: Example 14
5-Bromo-2-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Bromo-2-methylaniline manufacturers
- Product
- 5-Bromo-2-methylaniline 39478-78-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- 5-Bromo-2-methylaniline 39478-78-9
- Price
- US $40.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-28
- Product
- 5-Bromo-2-methylaniline 39478-78-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2020-01-16