5-Bromo-2-(trifluoromethyl)aniline
- Product Name
- 5-Bromo-2-(trifluoromethyl)aniline
- CAS No.
- 703-91-3
- Chemical Name
- 5-Bromo-2-(trifluoromethyl)aniline
- Synonyms
- 5-Bromo-2-(trifluoro;2-AMino-4-broMobenzotrifluoride;5-BROMO-2-(TRIFLUOROMETHYL)ANILINE;5-BROMO-O-(TRIFLUOROMETHYL)ANILINE;2-Amino-4-bromobenzotrifluoride 98%;5-BroMo-2-trifluoroMethyl-phenylaMine;5-Bromo-2-(trifluoromethyl)benzenamine;Benzenamine, 5-bromo-2-(trifluoromethyl)-;5-Bromo-2-(trifluoromethyl)aniline, 5-Bromo-alpha,alpha,alpha-trifluoro-o-toluidine
- CBNumber
- CB8439307
- Molecular Formula
- C7H5BrF3N
- Formula Weight
- 240.02
- MOL File
- 703-91-3.mol
5-Bromo-2-(trifluoromethyl)aniline Property
- Boiling point:
- 84-86 °C(Press: 5 Torr)
- Density
- 1.712 g/cm3(Temp: 25 °C)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 0.39±0.10(Predicted)
- Appearance
- Pale purple to purple Solid
Safety
- HS Code
- 2921430090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B809945
- Product name
- 5-Bromo-2-(Trifluoromethyl)aniline
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3830-B-14
- Product name
- 2-Amino-4-bromobenzotrifluoride
- Purity
- 98%
- Packaging
- 5G
- Price
- $82
- Updated
- 2021/12/16
- Product number
- 072933
- Product name
- 5-Bromo-2-(trifluoromethyl)aniline
- Purity
- 95+%
- Packaging
- 5g
- Price
- $156
- Updated
- 2021/12/16
- Product number
- 3830-B-14
- Product name
- 2-Amino-4-bromobenzotrifluoride
- Purity
- 98%
- Packaging
- 25g
- Price
- $216
- Updated
- 2021/12/16
- Product number
- 072933
- Product name
- 5-Bromo-2-(trifluoromethyl)aniline
- Purity
- 95+%
- Packaging
- 25g
- Price
- $489
- Updated
- 2021/12/16
5-Bromo-2-(trifluoromethyl)aniline Chemical Properties,Usage,Production
Synthesis
251115-21-6
703-91-3
General procedure for the synthesis of 5-bromo-2-(trifluoromethyl)aniline from 4-bromo-2-nitro-trifluoromethylbenzene: to a suspension of 4-bromo-2-nitro-1-(trifluoromethyl)benzene (4.0 g, 14.9 mmol) in ethanol (230 mL), THF (85 mL), and water (40 mL), ammonium chloride (1.0 g, 18.8 mmol) and iron powder (5.06 g, 90 mmol). The reaction mixture was heated at 80 °C for 1 h and the progress of the reaction was monitored by thin layer chromatography (TLC). After complete consumption of starting materials, the reaction mixture was filtered while hot. The filtrate was concentrated under reduced pressure and the crude product was dissolved in ethyl acetate (100 mL) and washed with water (3 x 50 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 5-bromo-2-(trifluoromethyl)aniline as a solid (3.2 g, 90% yield).
References
[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 100
[2] Patent: WO2014/149164, 2014, A1. Location in patent: Paragraph 00763; 00895
5-Bromo-2-(trifluoromethyl)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Bromo-2-(trifluoromethyl)aniline manufacturers
- Product
- 5-Bromo-2-(trifluoromethyl)aniline 703-91-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.3%
- Supply Ability
- 100 tons
- Release date
- 2022-02-20
- Product
- 5-Bromo-2-(trifluoromethyl)aniline 703-91-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08