methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate

Product Name: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
CAS No.: 1902955-29-6
Chemical Name: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Synonyms: Fexuprazan P-4;Fexuprazan Impurity3;Abeprazan Impurity 1;Fexuprazan intermediate;Methyl 5-(2,4-Difluorophenyl)-4-methoxypyrrole-3-carboxylate;methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate;1H-Pyrrole-3-carboxylic acid, 5-(2,4-difluorophenyl)-4-methoxy-, methyl ester;5-?(2,?4-?difluorophenyl)?-?4-?methoxy-?1H-?Pyrrole-?3-?carboxylic acid methyl ester;2-Butenoicacid,2-hydroxy-4-[3-methyl-4-(phenylmethoxy)phenyl]-4-oxo-,methylester,(5Z)-
CBNumber: CB94663743
Molecular Formula: C13H11F2NO3
Formula Weight: 267.23
MOL File: 1902955-29-6.mol

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methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Property

Boiling point:: 409.4±45.0 °C(Predicted)
Density: 1.314±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
pka: 13.95±0.50(Predicted)
Appearance: White to yellow Solid
InChI: InChI=1S/C13H11F2NO3/c1-18-12-9(13(17)19-2)6-16-11(12)8-4-3-7(14)5-10(8)15/h3-6,16H,1-2H3
InChIKey: DMNUDNHYRCDZDC-UHFFFAOYSA-N
SMILES: N1C(C2=CC=C(F)C=C2F)=C(OC)C(C(OC)=O)=C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ambeed

Product number: A941869
Product name: Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Purity: 98%
Packaging: 100mg
Price: $33
Updated: 2021/12/16

Ambeed

Product number: A941869
Product name: Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Purity: 98%
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Ambeed

Product number: A941869
Product name: Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Purity: 98%
Packaging: 1g
Price: $155
Updated: 2021/12/16

Chemenu

Product number: CM333146
Product name: Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Purity: 95%+
Packaging: 1g
Price: $216
Updated: 2021/12/16

Ambeed

Product number: A941869
Product name: Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
Purity: 98%
Packaging: 5g
Price: $557
Updated: 2021/12/16

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methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate is used as an intermediate for fexuprazan, a novel potassium-competitive acid blocker for the treatment of gastroesophageal reflux disease (GERD).

Synthesis

Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate can be prepared by the following routes^[1]:

References

[1] TING WANG. Scalable Synthesis of the Key Fexuprazan Intermediate and Investigation of a Reaction Mechanism.[J]. ACS Omega, 2024, 9 36: 37942-37952. DOI:10.1021/acsomega.4c04507.

methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Preparation Products And Raw materials

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methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Suppliers

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View Lastest Price from methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: 5-(2,4-difluorophenyl)-4-methoxy-1H-Pyrrole-3-carboxylic acid methyl ester 1902955-29-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-09-22

Hebei Chuanghai Biotechnology Co., Ltd

Product: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate 1902955-29-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

Beijing Toachem Chemical Co.,Ltd

Product: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate 1902955-29-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 30t
Release date: 2025-01-06

1902955-29-6, methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylateRelated Search:

methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate

1H-Pyrrole-3-carboxylic acid, 5-(2,4-difluorophenyl)-4-methoxy-, methyl ester

5-?(2,?4-?difluorophenyl)?-?4-?methoxy-?1H-?Pyrrole-?3-?carboxylic acid methyl ester

2-Butenoicacid,2-hydroxy-4-[3-methyl-4-(phenylmethoxy)phenyl]-4-oxo-,methylester,(5Z)-

Methyl 5-(2,4-Difluorophenyl)-4-methoxypyrrole-3-carboxylate

Fexuprazan intermediate

Fexuprazan P-4

Abeprazan Impurity 1

Fexuprazan Impurity3

1902955-29-6