4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
- Product Name
- 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
- CAS No.
- 108237-91-8
- Chemical Name
- 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
- Synonyms
- RCGD423;RCGD 432;N-(4-Bromophenyl)-4-phenylthiazol-2-amine;2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-;4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine;Regulator of cartilage growth and differentiation (RCGD) 423;RCGD423,inhibit,RCGD 423,Inhibitor,Interleukin Related,RCGD-423
- CBNumber
- CB94664083
- Molecular Formula
- C15H11BrN2S
- Formula Weight
- 331.23
- MOL File
- 108237-91-8.mol
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)
Ethanol:34.0(Max Conc. mg/mL);102.6(Max Conc. mM) - form
- A solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 7066
- Product name
- RCGD423
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $125
- Updated
- 2021/12/16
- Product number
- CS-0064289
- Product name
- RCGD423
- Purity
- 99.78%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-0064289
- Product name
- RCGD423
- Purity
- 99.78%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CS-0064289
- Product name
- RCGD423
- Purity
- 99.78%
- Packaging
- 25mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0064289
- Product name
- RCGD423
- Purity
- 99.78%
- Packaging
- 50mg
- Price
- $290
- Updated
- 2021/12/16
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Chemical Properties,Usage,Production
Biological Activity
RCGD-423 is a Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) signaling regulator that regulates cartilage growth and differentiation.
in vitro
RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.
in vivo
RCGD423 greatly reduces chondrocyte hypertrophy, loss and degeneration while increasing chondrocyte proliferation beyond that observed in response to injury in a rat partial meniscectomy model. Moreover, RCGD 423 improves cartilage healing in a rat full-thickness osteochondral defect model,
target
| IL6-beta < span> |
storage
Store at -20°C
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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