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N6-(4-Trifluoromethylbenzyl)adenosine

Product Name
N6-(4-Trifluoromethylbenzyl)adenosine
CAS No.
722505-71-7
Chemical Name
N6-(4-Trifluoromethylbenzyl)adenosine
Synonyms
N6-(4-Trifluoromethylbenzyl)adenosine;Adenosine, N-?[[4-?(trifluoromethyl)?phenyl]?methyl]?-;(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber
CB94672527
Molecular Formula
C18H18F3N5O4
Formula Weight
425.36
MOL File
722505-71-7.mol
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N6-(4-Trifluoromethylbenzyl)adenosine Property

Melting point:
151-153 °C
Boiling point:
675.9±65.0 °C(Predicted)
Density 
1.70±0.1 g/cm3(Predicted)
pka
13.11±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N6-(4-Trifluoromethylbenzyl)adenosine Chemical Properties,Usage,Production

Uses

N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

N6-(4-Trifluoromethylbenzyl)adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-(4-Trifluoromethylbenzyl)adenosine Suppliers

BOC Sciences
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16314854226; +16314854226
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TargetMol Chemicals Inc.
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+1-781-999-5354;
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support@targetmol.com
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722505-71-7, N6-(4-Trifluoromethylbenzyl)adenosineRelated Search:


  • N6-(4-Trifluoromethylbenzyl)adenosine
  • Adenosine, N-?[[4-?(trifluoromethyl)?phenyl]?methyl]?-
  • (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
  • 722505-71-7