ChemicalBook > CAS DataBase List > LUCIDIN

LUCIDIN

Product Name
LUCIDIN
CAS No.
478-08-0
Chemical Name
LUCIDIN
Synonyms
henine;LUCIDIN;CS-1096;NSC 30546;Lucidin-RM;Lucidin, BR;Lucidin【quinone】;HENINE; NSC 30546;NSC 30546|||Henine;Lucidin (NSC 30546)
CBNumber
CB9475944
Molecular Formula
C15H10O5
Formula Weight
270.24
MOL File
478-08-0.mol
More
Less

LUCIDIN Property

Melting point:
>330℃
Boiling point:
333.35°C (rough estimate)
Density 
1.592±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.6000 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
form 
Solid
pka
6.83±0.20(Predicted)
color 
Light yellow to yellow
More
Less

Safety

Hazardous Substances Data
478-08-0(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Usbiological
Product number
361821
Product name
Lucidin
Packaging
10mg
Price
$632
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001996
Product name
LUCIDIN
Purity
95.00%
Packaging
5MG
Price
$499.62
Updated
2021/12/16
ApexBio Technology
Product number
A3562
Product name
Lucidin
Packaging
10mg
Price
$541
Updated
2021/12/16
AK Scientific
Product number
3789AH
Product name
Lucidin
Packaging
50mg
Price
$1207
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181034
Product name
Lucidin (NSC 30546)
Purity
>98%
Packaging
250mg
Price
$1356.6
Updated
2021/12/16
More
Less

LUCIDIN Chemical Properties,Usage,Production

Definition

ChEBI: Lucidin is a dihydroxyanthraquinone.

Biological Activity

lucidin (nsc 30546) is a natural component of rubia tinctorum l., which is mutagenic in bacteria and mammalian cells [1].hydroxyanthraquinones (has) are special organic compounds widely distributed in the plant kingdom. the ha plants have been used as laxatives and colorant for thousands of years. in the last century, has were also employed as medicine for the treatment of kidney stone. lucidin is a ha extracted from the root of rubia tinctorum l. that also known as madder. it was thought to be genotoxic in bacteria and mammalian cells [1].lucidin was found to be mutagenic in five salmonella typhimurium strains without metabolic activation. additionally, in chinese hamster fibroblast v79 cells, lucidin was found to be mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus, which induced dna single-strand breaks and dna-protein cross-link. in primary rat hepatocytes and transformed c3h/ m2-mouse fibroblasts, it was observed lucidin might induce dna repair synthesis [1].in mouse model, when aci rats were treated with 1-10% madder roots in the diet and control group without madder roots for 780 days, the dose-dependent increase of benign and malignant tumors were observed in liver and kidney. additionally, dna adducts were observed in liver, kidney and colon when treated with 10% madder root for two weeks. the formation of dna adducts and mutagenicity was thought to be associated with lucidin which was contained in the madder roots [2].

References

[1] westendorf j et al. , the genotoxicity of lucidin, a natural component of rubia tinctorum l., and lucidinethylether, a component of ethanolic rubia extracts. cell biol toxicol. 1988, 4(2):225-239.
[2] westendorf j et al. , carcinogenicity and dna adduct formation observed in aci rats after long-term treatment with madder root, rubia tinctorum l. carcinogenesis. 1998, 19(12):2163-2168.

LUCIDIN Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

LUCIDIN Suppliers

Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
More
Less

View Lastest Price from LUCIDIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Lucidin 478-08-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-15
Career Henan Chemical Co
Product
LUCIDIN 478-08-0
Price
US $8.00/KG
Min. Order
1KG
Purity
>98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

478-08-0, LUCIDINRelated Search:


  • 1,3-dihydroxy-2-(hydroxymethyl)-10-anthracenedione
  • 1,3-dihydroxy-2-hydroxymethylanthraquinoline
  • 1,3-dihydroxy-2-hydroxymethyl-anthraquinon
  • henine
  • 1,3-DIHYDROXY-2-(HYDROXYMETHYL)ANTHRAQUINONE
  • LUCIDIN
  • 1,3-Dihydroxy-2-hydroxymethylanthracene-9,10-dione
  • Lucidin【quinone】
  • 1,3-dihydroxy-2-methylol-9,10-anthraquinone
  • 1,3-Dihydroxy-2-hydroxyMethyl-9,10-anthracenedione, 9CI
  • HENINE; NSC 30546
  • CS-1096
  • Lucidin (NSC 30546)
  • Lucidin, BR
  • NSC 30546
  • 9,10-Anthracenedione,1,3-dihydroxy-2-(hydroxymethyl)-
  • NSC 30546|||Henine
  • Lucidin-RM
  • 478-08-0
  • Anthraquinones