2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID

Product Name: 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID
CAS No.: 25178-38-5
Chemical Name: 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID
Synonyms: 2-HYDROXY PHENYL GLYCINE;2-(2-Hydroxyphenyl)glycine;2-amino-2-(2-hydroxyphenyl);α-Amino-2-hydroxybenzeneacetic Acid;2-Amino(2-hydroxyphenyl)acetic acid;AMINO-(2-HYDROXY-PHENYL)-ACETIC ACID;2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID;Benzeneacetic acid, a-amino-2-hydroxy-;Benzeneacetic acid, α-amino-2-hydroxy-;2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID USP/EP/BP
CBNumber: CB9475979
Molecular Formula: C8H9NO3
Formula Weight: 167.16
MOL File: 25178-38-5.mol

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2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID Property

Boiling point:: 358.8±32.0 °C(Predicted)
Density: 1.396±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka: 1.82±0.10(Predicted)
form: Solid
color: White to Pale Red
Stability:: Hygroscopic

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2922500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A580015
Product name: α-Amino-2-hydroxybenzeneaceticAcid
Packaging: 100mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA155066
Product name: 2-Amino-2-(2-hydroxyphenyl)acetic acid
Packaging: 50mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA155066
Product name: 2-Amino-2-(2-hydroxyphenyl)acetic acid
Packaging: 100mg
Price: $160
Updated: 2021/12/16

Activate Scientific

Product number: AS37179
Product name: 2-Amino-2-(2-hydroxyphenyl)acetic acid
Purity: 95+%
Packaging: 1g
Price: $212
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA155066
Product name: 2-Amino-2-(2-hydroxyphenyl)acetic acid
Packaging: 250mg
Price: $250
Updated: 2021/12/16

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2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID Chemical Properties,Usage,Production

Uses

α-Amino-2-hydroxybenzeneacetic Acid was studied for its role in treating, preventing or improving nonalcoholic fatty liver disease.

Synthesis

a) Salicylaldehyde and benzylamine (molar ratio 1:1) were dissolved in ethanol and the mixture was refluxed for 2 hours. The reaction was stirred at room temperature for an additional 2 h. The solvent was removed under reduced pressure to give the imine in quantitative yield. b) To the above obtained imine was added anhydrous tetrahydrofuran (THF), trimethylcyanosilane (TMSCN) was slowly added dropwise with a molar ratio iminization: TMSCN of 1: 3. The reaction mixture was stirred at room temperature for 40 h. The reaction mixture was added to a solution of saturated ammonium chloride followed by (NH4Cl), extracted with ether, the ether phase was washed with water, and finally dried with magnesium sulphate, and solvent was removed under vacuum, and it was ??-aminonitrile is obtained quantitatively as an oil. c) The obtained ??-aminonitrile is heated in concentrated hydrochloric acid at 60-70??C for 3 hours. Thereafter, the crude oil was allowed to cool and dried under reduced pressure. After drying, the residue was suspended in acetone, filtered and dried to give N-benzyl-2-hydroxyphenylglycine hydrochloride as a powdered solid in 97% yield. d) To a methanolic solution of (15% by weight in mass of substrate)-benzyl-2-hydroxyphenylglycine N was added a solution of hydrochloric acid in Pd (c) and then carried out under hydrogen pressure (50 psi) for 16 hours. The crude product was filtered and the solvent was removed under reduced pressure to give 2-hydroxyphenylglycine in 96% yield.

2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID Suppliers

China 63 India 3 United Kingdom 4 United States 15 Global 85

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View Lastest Price from 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID manufacturers

Career Henan Chemical Co

Product: 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID 25178-38-5
Price: US $5.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

25178-38-5, 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACIDRelated Search:

Ethylenediamine-N,N'-bis((2-hydroxyphenyl)acetic acid) 4-Hydroxy-D-(-)-2-phenylglycine D(-)-2-[[(4-ETHYL-2,3-DIOXOPIPERAZINYL)CARBONYL]AMINO]-2-(4-HYDROXYPHENYL)ACETIC ACID 2-(BOC-AMINO)-2-(4'-HYDROXYPHENYL)ACETIC ACID (2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid AMOXICILLIN TRIHYDRATE IMP. I (EP): (2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETIC ACID 2-Hydroxyphenylacetic acid 2-(4-BOC-PIPERAZINYL)-2-(2-METHOXY-PHENYL)ACETIC ACID 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID AMINO-(2,4,5-TRIMETHOXY-PHENYL)-ACETIC ACID AMINO-(2-BENZYLOXY-PHENYL)-ACETIC ACID GAMMA-METHYL-L-LEUCINE 2-AMINO-2-(2-ETHOXYPHENYL)ACETIC ACID (R)-2-METHOXY-PHENYLGLYCINE AMINO-(2,3,4-TRIMETHOXY-PHENYL)-ACETIC ACID AMINO(5-BROMO-2-METHOXYPHENYL)ACETIC ACID AMINO-(2-METHOXY-NAPHTHALEN-1-YL)-ACETIC ACID AMINO-(2,3-DIMETHOXY-PHENYL)-ACETIC ACID

2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID

2-HYDROXY PHENYL GLYCINE

AMINO-(2-HYDROXY-PHENYL)-ACETIC ACID

2-Amino(2-hydroxyphenyl)acetic acid

Benzeneacetic acid, a-amino-2-hydroxy-

2-(2-Hydroxyphenyl)glycine

(S)-methyl 2-(2-chlorophenyl)-2-(2-(hydroxymethyl)-6,7- dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate

Benzeneacetic acid, α-amino-2-hydroxy-

2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID USP/EP/BP

α-Amino-2-hydroxybenzeneacetic Acid

2-amino-2-(2-hydroxyphenyl)

25178-38-5

pharmacetical