(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

Product Name: (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
CAS No.: 62893-24-7
Chemical Name: (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
Synonyms: HO-EPCP;OH-EPCP;Dioxypiperazine acid;Oxygen piperazine acid;Cefoperazone Impurity 2;2R-2-((4-ethyl-2,3-dioxypipera;2-(4 hydroxyphenyl)acetic acid HO-EPCP;4-(2,3-Dioxopiperazin-1-yl)benzoylpiperazine-2,5-dione;2R-2-((4-ETHYL-2,3-DIOXYPIPERAZYL)FORMAMIDE)-4-HYDROXYPHENYLACETICACID;(R)-(-)-alpha-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)nh)-4-OH-ben
CBNumber: CB4278184
Molecular Formula: C15H17N3O6
Formula Weight: 335.32
MOL File: 62893-24-7.mol

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(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Property

Melting point:: 205 °C (dec.) (lit.)
alpha: -0.85 º(c=1,MeOH)
Boiling point:: 471.96°C (rough estimate)
Density: 1.2546 (rough estimate)
refractive index: 1.5600 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Sparingly)
form: Solid
pka: 3.40±0.10(Predicted)
color: White to Off-White
optical activity: [α]20/D 85°, c = 1 in methanol
InChI: InChI=1/C15H17N3O6/c1-2-17-7-8-18(13(21)12(17)20)15(24)16-11(14(22)23)9-3-5-10(19)6-4-9/h3-6,11,19H,2,7-8H2,1H3,(H,16,24)(H,22,23)/t11-/s3
InChIKey: IPARGUVYMOMVNU-LBPXTSNRNA-N
SMILES: C(N1CCN(CC)C(=O)C1=O)(=O)N[C@H](C1C=CC(O)=CC=1)C(=O)O |&1:13,r|
CAS DataBase Reference: 62893-24-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 2933.59.8000
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 472905
Product name: (R)-(?)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid
Purity: 97%
Packaging: 5g
Price: $182
Updated: 2023/06/20

TCI Chemical

Product number: E0994
Product name: (R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $17
Updated: 2026/03/19

TCI Chemical

Product number: E0994
Product name: (R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $38
Updated: 2026/03/19

TRC

Product number: E917365
Product name: (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneaceticAcid
Packaging: 25g
Price: $175
Updated: 2021/12/16

AK Scientific

Product number: C972
Product name: (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)aceticacid
Packaging: 250mg
Price: $70
Updated: 2021/12/16

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(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

(αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria.

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Preparation Products And Raw materials

Raw materials

Acetone Sodium sulfate Sodium chloride 4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride Chlorotrimethylsilane Ethyl acetate Dichloromethane 4-Hydroxy-D-(-)-2-phenylglycine Hexamethyldisilazane 1-Butanol

Preparation Products

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(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid Suppliers

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View Lastest Price from (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid manufacturers

Career Henan Chemical Co

Product: (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid 62893-24-7
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-21

62893-24-7, (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acidRelated Search:

Ethyl cyanoacetate 3-Diethylaminophenol Ethylparaben PIPERAZINE CITRATE HYDRATE Piperacillin 1-Hydroxyethylidene-1,1-diphosphonic acid Ethyl acetate ISOXADIFEN-ETHYL Trinexapac-ethyl Ethyl acrylate Ethyl propiolate N-Aminoethylpiperazine (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-phenylacetic acid 2-Ethylhexyl ferulate 1,4-Dioxane Selenium dioxide Ethanol 5-Mercapto-1-methyltetrazole

(R)-(-)-ALPHA-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXYBENZENEACETIC ACID

(R)-(-)-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXYBENZENEACETIC ACID

D-(-)-A-(4-ETHYL-2,3-DIOXO PIPERZINYL) CARBOCAMIDE-4-HYDROXYPHENYL-ACETIC ACID

D-(-)-2-(2,3-DIOXO-4-ETHYL-1-PIPERAZIN-CARBOXAMIDE)-ALPHA-4-HYDROXY PHENYL ACETIC ACID

D-(-)-2-[(4-ETHYL-2,3-DIOXO-1-PIPERAZINEYL)-CARBONYLAMINO]-2-(4-HYDROXYPHENYL) ACETIC ACID

2R-2-((4-ETHYL-2,3-DIOXYPIPERAZYL)FORMAMIDE)-P-HYDROXY PHENYLACETIC ACID

(2R)-2-[(4-ETHYL-2,3-DIOXOPIPERAZINYL)CARBONYLAMINO]-2-(4-HYDROXYPHENYL)ACETIC ACID

N-((4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL)-A-AMINO-P- HYDROXYPHENYLACETIC ACID

2R-2-((4-ethyl-2,3-dioxypipera

D(-)-2-[[(4-ETHYL-2,3-DIOXOPIPERAZINYL)CARBONYL]AMINO]-2-(4-HYDROXYPHENYL)ACETIC ACID

HO-EPCP D-(-)-A-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXYBENZENEACET

2R-2-((4-ETHYL-2,3-DIOXYPIPERAZYL)FORMAMIDE)-4-HYDROXYPHENYLACETICACID

( R ) -2-[(4-Ethyl-2,3-dioxo-1-piperazinyl) carbonylamino]-2-(4-hydroxyphenyl)acetic acid

N-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-4-hydroxybenzeneacetic acid

N-((4-Ethyl-2,3-dioxo-1-piperazinyl)car-bonyl)-amino-p-hydroxyphenylacetic acid

{[(2,3-Dioxo-4-ethyl-1-piperazinyl)-carbonyl]-amino}-(4-hydroxyphenyl)-acet

BENZENEACETICACID,A-[[(4-ETHYL-2,3-DIOXO-1-PIPERAZINYL)CARBONYL]AMINO]-4-HYDROXY-(9CI)

[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino](4-hydroxyphenyl)acetic acid

(R)-(-)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenz

D(-)-2[(4-ehtyl-2,3-dioxo-1-piperazineyl)-carbonylamino]-2-(4-hydroxyphenyl)acetic acid

(R)-(-)-A-(((4-ETHYL-2,3-DIOXO-1-PIPERAZ IN -YL)CARBONYL)AMINO)-4-OH-BENZENEACETI

HO-EPCP:D-(-)-2-[(4-ETHYL-2,3-DIOXO-1-PIPERAZINEYL)-CARBONYLAMINO] -2-(4-HYDROXYPHENYL) ACETIC ACID

OH-EPCP

D(-)-a-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)Carbonyl]Amino]-2-(4-Hydroxyphenyl)AceticAcid

(R)-(-)-a-(((4-Ethyl-2,3-dioxo-1-piperazin-yl)carbonyl)nh)-4-oh-benzeneaceticacid

HO-EPCP

(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)-oxomethyl]amino]-2-(4-hydroxyphenyl)acetate

(<i>R</i>)-(-)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic Acid

Benzeneacetic acid, a-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]aMino]-4-hydroxy-,(aR)-

(R)-(-)-alpha-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)nh)-4-OH-benzene acetic acid

(R)-(-)-alpha-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)nh)-4-OH-ben

2-(4 hydroxyphenyl)acetic acid HO-EPCP

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid,97%

(R)-(-)-[[(4-Ethyl-2,3-dioxo-1-piperzinyl)carbonyl]amino]-4-hydroxybenzenacetic Acid

(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid 97%

(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetic acid

Cefoperazone Impurity 2

(D-)-Alpha-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl) Carbonyl]Amino]-2-(4-Hydroxyphenyl) Acetic Acid

(R)-(-)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneaceticAcid&gt

Benzeneacetic acid, α-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-, (αR)-

(R)-(-)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid

(αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid

(iRi)-(-)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneaceticAci

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid ISO 9001：2015 REACH

D(-)-α-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl) acetic acid

2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetic acid compound with acetic acid (1:1)

Oxygen piperazine acid

Dioxypiperazine acid

(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid (OH-EPCP)

(<i>R</i>)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetic acid

4-(2,3-Dioxopiperazin-1-yl)benzoylpiperazine-2,5-dione

(R)-(?)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid,(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid

(AlphaR)-Alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid

62893-24-7

C15H17N3O6

C15H16N3O6

Asymmetric Synthesis

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