N-METHYLISATIN

Product Name: N-METHYLISATIN
CAS No.: 2058-74-4
Chemical Name: N-METHYLISATIN
Synonyms: OL-57;187287;NSC 42449;AKOS BC-1698;N-Methylsatin;1-METHYLISATIN;N-METHYLISATIN;1 METHYLISATINE;Methylisatintech;AKOS BBS-00000999
CBNumber: CB9480285
Molecular Formula: C9H7NO2
Formula Weight: 161.16
MOL File: 2058-74-4.mol

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N-METHYLISATIN Property

Melting point:: 130-133 °C (lit.)
Boiling point:: 287.44°C (rough estimate)
Density: 1.314
refractive index: 1.5050 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: -2.41±0.20(Predicted)
form: Crystalline Powder
color: Orange to brownish
Water Solubility: Insoluble in water.
λmax: 427nm(CH2Cl2)(lit.)
BRN: 128280
CAS DataBase Reference: 2058-74-4(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25-37/38-41
Safety Statements: 26-39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NL7939000
HazardClass: IRRITANT
HS Code: 29337900
Toxicity: mouse,LD50,intraperitoneal,685mg/kg (685mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Pharmaceutical Chemistry Journal Vol. 15, Pg. 858, 1981.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 1g
Price: $41.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 10g
Price: $82.4
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 1g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 5g
Price: $111
Updated: 2024/03/01

Alfa Aesar

Product number: A12942
Product name: 1-Methylisatin, 97%
Packaging: 1g
Price: $35.65
Updated: 2024/03/01

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N-METHYLISATIN Chemical Properties,Usage,Production

Chemical Properties

ORANGE TO BROWNISH CRYSTALLINE POWDER

Uses

1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.

Uses

Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
Reactant for regioselective preparation of spirocyclic oxindole-butenolides
Reactant for synthesis of spiro-oxindoles
Reactant for preparation of unsymmetrical oxindoles
Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Synthesis Reference(s)

Journal of Medicinal Chemistry, 47, p. 2089, 2004 DOI: 10.1021/jm030483s

General Description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

N-METHYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYLISATIN Suppliers

Americas 1 Belgium 3 China 81 Europe 1 France 1 Germany 7 India 13 Japan 2 Russia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 15 United States 25 Global 155

Hotechem Shanghai Co., Ltd.,

Tel: 021-34621078 13120882795
Fax: 021-34622517
Email: 465106944@qq.com
Country: China
ProdList: 858
Advantage: 56

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 21-31038972 15721252604
Fax: +86-21-51385350
Email: ammyzuo@harvest-chem.com
Country: China
ProdList: 2511
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

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View Lastest Price from N-METHYLISATIN manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methylisatin 97% 2058-74-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: N-METHYLISATIN 2058-74-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-01-29

2058-74-4, N-METHYLISATINRelated Search:

3-(1-methyl-1H-indole-3-carbonyl)hexanedioic acid (3R)-2,3-Dihydro-3-(2-propyn-1-ylaMino)-1H-inden-1-one 1-Methyl-1H-indole-3-carboxylic acid 1-Methylindole Ramosetron hydrochloride Rasagiline Impurity 5 Mesylate 5-(1-methyl-1H-indole-3-carbonyl)-1H-benzo[d]imidazol-2(3H)-one ramosetron 4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride Rasagiline Impurity 3 3a,7a-dihydroxy-5-(1-methyl-1H-indole-3-carbonyl)-hexahydro-1H-benzo[d]imidazol-2(3H)-one Ramosetron Impurity 13 N-[4,5,6,7-Tetrahydrobenzimidazole-5-yl)carbonyl] pyrrolidine sulfate 1-PHENYLISATIN 1-(Hydroxymethyl)indoline-2,3-dione N-METHYLISATIN 1,5-DIMETHYLINDOLINE-2,3-DIONE 5-CHLORO-7-METHYLISATIN

187287

1-methylindoline-2,3-dione

1-Methyl-2,3-dihydro-1H-indole-2,3-dione

OL-57

N-Methylindol-2,3-dione

1-Methylisatin,98%

N-Methylindoline-2,3-dione

1-Methyl-1H-indole-2,3-dione, 1-Methylindolin-2,3-dione

1-Methylisatin 97+%

1-Methylisatin 97%

NSC 42449

1H-Indole-2,3-dione, 1-methyl- (9CI)

1H-Indole-2,3-dione, 1-Methyl-

Indole-2,3-dione, 1-methyl-

Ramosetron Impurity 1

1-methyl-1h-indole-3-dione

1-methyl-indole-2,3-dione

1-methyl-indole-3-dione

1-METHYL-1H-INDOLE-2,3-DIONE

1 METHYLISATINE

1-METHYLISATIN

N-METHYLISATIN

TIMTEC-BB SBB006835

1-methyl-2,3-dihydroindole-2,3-dione

Methylisatintech

N-Methylsatin

N-Methylisatin, tech.

N-Methylisatin 98%

AKOS BBS-00000999

AKOS BC-1698

1-Methylisatin, 97%, for synthesis

1-Methylisatin &gt

1-Methylindoline-2,3-dione (Ramosetron Impurity)

2058-74-4

Indoles

Heterocyclic Building Blocks

Building Blocks

Heterocycles

Building Blocks

Heterocyclic Building Blocks

Indoles

pharmacetical