ChemicalBook > CAS DataBase List > N-METHYLISATIN

N-METHYLISATIN

Product Name
N-METHYLISATIN
CAS No.
2058-74-4
Chemical Name
N-METHYLISATIN
Synonyms
OL-57;187287;NSC 42449;AKOS BC-1698;N-Methylsatin;1-METHYLISATIN;N-METHYLISATIN;1 METHYLISATINE;Methylisatintech;AKOS BBS-00000999
CBNumber
CB9480285
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
2058-74-4.mol
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N-METHYLISATIN Property

Melting point:
130-133 °C (lit.)
Boiling point:
287.44°C (rough estimate)
Density 
1.314
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
-2.41±0.20(Predicted)
form 
Crystalline Powder
color 
Orange to brownish
Water Solubility 
Insoluble in water.
λmax
427nm(CH2Cl2)(lit.)
BRN 
128280
CAS DataBase Reference
2058-74-4(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25-37/38-41
Safety Statements 
26-39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
NL7939000
HazardClass 
IRRITANT
HS Code 
29337900
Toxicity
mouse,LD50,intraperitoneal,685mg/kg (685mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Pharmaceutical Chemistry Journal Vol. 15, Pg. 858, 1981.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
183075
Product name
1-Methylisatin
Purity
97%
Packaging
1g
Price
$41.6
Updated
2024/03/01
Sigma-Aldrich
Product number
183075
Product name
1-Methylisatin
Purity
97%
Packaging
10g
Price
$82.4
Updated
2024/03/01
TCI Chemical
Product number
M2706
Product name
1-Methylisatin
Purity
>98.0%(GC)
Packaging
1g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
M2706
Product name
1-Methylisatin
Purity
>98.0%(GC)
Packaging
5g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
A12942
Product name
1-Methylisatin, 97%
Packaging
1g
Price
$35.65
Updated
2024/03/01
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N-METHYLISATIN Chemical Properties,Usage,Production

Chemical Properties

ORANGE TO BROWNISH CRYSTALLINE POWDER

Uses

1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.

Uses

  • Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
  • Reactant for regioselective preparation of spirocyclic oxindole-butenolides
  • Reactant for synthesis of spiro-oxindoles
  • Reactant for preparation of unsymmetrical oxindoles
  • Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
  • Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Synthesis Reference(s)

Journal of Medicinal Chemistry, 47, p. 2089, 2004 DOI: 10.1021/jm030483s

General Description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

N-METHYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYLISATIN Suppliers

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View Lastest Price from N-METHYLISATIN manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Methylisatin 97% 2058-74-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
N-METHYLISATIN 2058-74-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-01-29

2058-74-4, N-METHYLISATINRelated Search:

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