ChemicalBook > CAS DataBase List > S(-)-RACLOPRIDE L-TARTRATE

S(-)-RACLOPRIDE L-TARTRATE

Product Name
S(-)-RACLOPRIDE L-TARTRATE
CAS No.
84225-95-6
Chemical Name
S(-)-RACLOPRIDE L-TARTRATE
Synonyms
RAC;SKL202;FLA-870;Racloprida;RACLOPRIDE;Raclopridum;Raclopride >Raclopridum [latin];Racloprida [spanish];Raclopride84225-95-6
CBNumber
CB9483923
Molecular Formula
C15H20Cl2N2O3
Formula Weight
347.24
MOL File
84225-95-6.mol
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S(-)-RACLOPRIDE L-TARTRATE Property

Melting point:
52.0 to 56.0 °C
Boiling point:
420.3±45.0 °C(Predicted)
Density 
1.288±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
H2O: 89 mg/mL
form 
solid
pka
5.93±0.50(Predicted)
color 
white
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
CV3465000
HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5.05877
Product name
(S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem
Packaging
10mg
Price
$111
Updated
2025/07/31
TCI Chemical
Product number
R0094
Product name
Raclopride
Purity
>98.0%(HPLC)(N)
Packaging
200mg
Price
$212
Updated
2025/07/31
TCI Chemical
Product number
R0094
Product name
Raclopride
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$717
Updated
2025/07/31
Cayman Chemical
Product number
17422
Product name
Raclopride
Purity
≥99%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
17422
Product name
Raclopride
Purity
≥99%
Packaging
10mg
Price
$82
Updated
2024/03/01
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S(-)-RACLOPRIDE L-TARTRATE Chemical Properties,Usage,Production

Description

Raclopride is a selective dopamine D2/D3 receptor antagonist with Ki values of 1.8, 3.5, 2,400, and 18,000 nM for D2, D3, D4, and D1 receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.

Chemical Properties

Yellowish solid

Uses

A labelled dopamine receptor

Uses

neuroleptic;selective dopamine D1/D2 receptors antagonist

Uses

Raclopride is a potent D2DR/D3DR antagonist.

Definition

ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.

Biological Activity

Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .

storage

Store at -20°C

References

[1] M S LIDOW. Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1989, 86 16: 6412-6416. DOI: 10.1073/pnas.86.16.6412
[2] GINOVART N. Imaging the dopamine system with in vivo [11C]raclopride displacement studies: understanding the true mechanism.[J]. Molecular Imaging and Biology, 2005, 7 1: 45-52. DOI: 10.1007/s11307-005-0932-0

S(-)-RACLOPRIDE L-TARTRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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84225-95-6, S(-)-RACLOPRIDE L-TARTRATERelated Search:

Loratadine Cisapride 3,5-DICHLOROSALICYLALDEHYDE 4,6-DICHLORORESORCINOL 4-Chlororesorcinol S(-)-RACLOPRIDE L-TARTRATE Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:) Diclometide (S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIHYDROXY-BENZAMIDE N-(5-chloro-2-methoxybenzyl)-N-ethylamine 2,4-Dichloro-5-methoxyphenol BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-6-METHOXY-, (S)- N-(3-CHLOROBENZYL)BUTAN-1-AMINE N-(5-CHLORO-2-METHOXYBENZYL)-N-METHYLAMINE 3,5-DICHLORO-2-HYDROXYBENZYLAMINE S(-)RACLOPRIDE L-TARTRATE >97% SELECTIVE D2 DOPAMINE N1-BENZYL-N2,N2-DIETHYL-1,2-PROPANEDIAMINE (S)-RACLOPRIDE, [METHOXY-3H]

  • (S)-3,5-dichloro-N-((1-ethylpyrrolidin -2-yl)methyl)-2-hydroxy-6- methoxybenzamide (2R,3R) -2,3-dihydroxysuccinate
  • (2S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)-METHYL]-6- METHOXYSALICYLAMIDE
  • BENZAMIDE, 3,5-DICHLORO-N-[[(2S)-1-ETHYL-2-PYRROLIDINYL]METHYL]-2-HYDROXY-6-METHOXY-
  • 3,5-Dichloro-N-[(2S)-1-ethyl-2-pyrrolidinyl]-2-hydroxy-6-methoxybenzamide
  • FLA-870
  • RAC
  • 3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-6-hydroxybenzamide
  • 3,5-Dichloro-N-[[(2S)-1-ethylpyrrolidine-2α-yl]methyl]2-hydroxy-6-methoxybenzamide
  • (-)-(S)-3,5-Dichlor-N-((1-ethyl-2-pyrrolidinyl)methyl)-6-hydroxy-o-anisamid
  • Benzamide, 3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-6-methoxy-, (-)-
  • Racloprida
  • Racloprida [spanish]
  • Raclopridum
  • Raclopridum [latin]
  • (S)-3,5-Dichloro-N-((1-ethylpyrrolidin-2-yl)Methyl)-2-hydroxy-6-MethoxybenzaMide
  • -2-hydroxy-6-methoxybenzamide
  • -3,5-Dichloro-N-((1-ethylpyrrolidin-2-yl)
  • RACLOPRIDE
  • S(-)-RACLOPRIDE L-TARTRATE
  • 3,5-DICHLORO-N-[[(2S)-1-ETHYL-2-PYRROLIDINYL]METHYL]-2-HYDROXY-6-METHOXYBENZAMIDE
  • (2S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]- 6-HYDROXY-2-METHOXYBENZAMIDE
  • Raclopride84225-95-6
  • Raclopride &gt
  • (S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide
  • S(-)-RACLOPRIDE L-TARTRATE ISO 9001：2015 REACH
  • SKL202
  • Raclopride (FLA-870)
  • inhibit,central,Dopamine Receptor,dopaminergic D2 receptor,Inhibitor,benzamide,antiaggressive,Raclopride
  • (S)-(-)-Raclopride, D2 receptor antagonist
  • Raclopride, 10 mM in DMSO
  • 84225-95-6
  • C15H16D5Cl3N2O3
  • C15H20Cl2N2O3C4H6O6
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Dopamine receptor