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Elexacaftor

Product Name
Elexacaftor
CAS No.
2216712-66-0
Chemical Name
Elexacaftor
Synonyms
VX445;Elexacaftor;Yilai Kapoor;Elexacaftor,VX445;lexacaftor (VX-445);Elexacaftor, 10 mM in DMSO;Elexacaftor (VX-445) ,S8851;Elexacaftor (VX-445, WHO-11180);Elexacaftor-D3Q: What is Elexacaftor-D3 Q: What is the CAS Number of Elexacaftor-D3;N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)
CBNumber
CB94848184
Molecular Formula
C26H34F3N7O4S
Formula Weight
597.65
MOL File
2216712-66-0.mol
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Elexacaftor Property

Melting point:
206 - 208°C
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
3.80±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
MVRHVFSOIWFBTE-INIZCTEOSA-N
SMILES
C1(N2C[C@@H](C)CC2(C)C)=NC(N2C=CC(OCC(C)(C)C(F)(F)F)=N2)=CC=C1C(NS(C1=CN(C)N=C1C)(=O)=O)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0090942
Product name
Elexacaftor
Purity
99.77%
Packaging
1mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0090942
Product name
Elexacaftor
Purity
99.77%
Packaging
5mg
Price
$980
Updated
2021/12/16
ChemScene
Product number
CS-0090942
Product name
Elexacaftor
Purity
99.77%
Packaging
10mg
Price
$1500
Updated
2021/12/16
ChemScene
Product number
CS-0090942
Product name
Elexacaftor
Purity
99.77%
Packaging
50mg
Price
$4500
Updated
2021/12/16
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Elexacaftor Chemical Properties,Usage,Production

Uses

Elexacaftor medication used in those that have cystic fibrosis with a f508del mutation.

Synthesis

Synthesis route of Elexacaftor

Elexacaftor Preparation Products And Raw materials

Raw materials

Preparation Products

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Elexacaftor Suppliers

Suzhou Zehou Biotechnology Co. , Ltd.
Tel
0512-68716880 19984816880
Fax
18075373931
Email
sales@growingchem.com
Country
China
ProdList
212
Advantage
64
Shanghai fuxiang biotechnology co., ltd
Tel
13611719524
Email
2674347328@qq.com
Country
China
ProdList
58
Advantage
58
ShangHai Onsyn-Chemical Technology Co., Ltd.
Tel
021-58359326 15900795984
Fax
+86-21-58359326
Email
angsihuaxue@126.com
Country
China
ProdList
252
Advantage
55
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Synmedia Chemical Co., Ltd.
Tel
021-38681880 13817889927
Fax
0213390-8196
Email
sales@synmedia-chem.com
Country
China
ProdList
249
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
7218
Advantage
58
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View Lastest Price from Elexacaftor manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Elexacaftor 2216712-66-0
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
50kg/Month
Release date
2024-06-28

2216712-66-0, ElexacaftorRelated Search:


  • Elexacaftor
  • N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
  • VX445
  • Elexacaftor,VX445
  • 3-Pyridinecarboxamide, N-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-
  • N-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-6-[3-(3,3 ,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-car boxamide
  • Elexacaftor-D3Q: What is Elexacaftor-D3 Q: What is the CAS Number of Elexacaftor-D3
  • N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)
  • Elexacaftor (VX-445, WHO-11180)
  • (S)-N-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide
  • lexacaftor (VX-445)
  • Fibrosis,Autophagy,VX445,CFTR,VX 445,Cystic fibrosis transmembrane conductance regulator,Inhibitor,Cystic,Elexacaftor,inhibit
  • Elexacaftor, 10 mM in DMSO
  • Elexacaftor (VX-445) ,S8851
  • Yilai Kapoor
  • 2216712-66-0
  • C26H34F3N7O4S