ChemicalBook > CAS DataBase List > USL-311
USL-311
- Product Name
- USL-311
- CAS No.
- 1373268-67-7
- Chemical Name
- USL-311
- Synonyms
- USL-311;USL311, 10 mM in DMSO;6-(4-(1-Isopropylpiperidin-4-yl)-1,4-diazepan-1-yl)-N-(pyridin-4-yl)picolinamide;USL 311,anti-tumor,CXC chemokine receptors,USL311,glioma,inhibit,CXCR,USL-311,Inhibitor;2-Pyridinecarboxamide, 6-[hexahydro-4-[1-(1-methylethyl)-4-piperidinyl]-1H-1,4-diazepin-1-yl]-N-4-pyridinyl-
- CBNumber
- CB94849040
- Molecular Formula
- C24H34N6O
- Formula Weight
- 422.57
- MOL File
- 1373268-67-7.mol
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USL-311 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 25 mg/mL (59.16 mM)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0080568
- Product name
- USL311
- Purity
- 99.97%
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0080568
- Product name
- USL311
- Purity
- 99.97%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0080568
- Product name
- USL311
- Purity
- 99.97%
- Packaging
- 50mg
- Price
- $850
- Updated
- 2021/12/16
DC Chemicals
- Product number
- 027674
- Product name
- USL-311
- Packaging
- 001
- Price
- $600
- Updated
- 2021/12/16
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USL-311 Chemical Properties,Usage,Production
Uses
USL311 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4[1].
IC 50
CXCR4
References
[1] Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1
[2] Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790. DOI:10.1016/j.pharmthera.2020.107790
USL-311 Preparation Products And Raw materials
Raw materials
Preparation Products
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USL-311 Suppliers
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