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2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE

Product Name
2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
CAS No.
28910-83-0
Chemical Name
2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
Synonyms
4-chloro-2-(2,6-difluorobenzoyl)aniline;2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE;2-Amino-5-chloro-2',6'-difluorobenzophenone 98%;2-Amino-5-chloro-2',6'-difluorobenzophenone 98+%;2-AMINO-5-CHLORO-PHENYL-(2-6-DIFLUORO-PHENYL)-METHANONE;Methanone, (2-amino-5-chlorophenyl)(2,6-difluorophenyl)-;6-benzoyl-4-chloro-1,5-difluorocyclohexa-2,4-dien-1-aMine;2-Amino-5-chloro-2′,6′-difluoro-benzophenone, CAS 28910-83-0
CBNumber
CB9489864
Molecular Formula
C13H8ClF2NO
Formula Weight
267.66
MOL File
28910-83-0.mol
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2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE Property

Melting point:
151-153°C
Boiling point:
435.2±45.0 °C(Predicted)
Density 
1.407±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-1.71±0.10(Predicted)
color 
Yellow
InChI
InChI=1S/C13H8ClF2NO/c14-7-4-5-11(17)8(6-7)13(18)12-9(15)2-1-3-10(12)16/h1-6H,17H2
InChIKey
DUMGVPIXKALANS-UHFFFAOYSA-N
SMILES
C(C1=CC(Cl)=CC=C1N)(C1=C(F)C=CC=C1F)=O
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Safety

HS Code 
2922390090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
A603325
Product name
2-Amino-5-chloro-2'',6''-difluoro-benzophenone
Packaging
100mg
Price
$50
Updated
2021/12/16
TRC
Product number
A603325
Product name
2-Amino-5-chloro-2'',6''-difluoro-benzophenone
Packaging
1g
Price
$110
Updated
2021/12/16
Apolloscientific
Product number
PC6424
Product name
2-Amino-5-chloro-2',6'-difluorobenzophenone
Purity
98%
Packaging
5g
Price
$138
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17622
Product name
2-Amino-5-chloro-2',6'-difluoro-benzophenone
Packaging
500mg
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
090374
Product name
(2-Amino-5-chlorophenyl)-(2,6-difluorophenyl)methanone
Purity
95+%
Packaging
1g
Price
$88
Updated
2021/12/16
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2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

2-Aminobenzophenone derivative.

Synthesis

869365-92-4

28910-83-0

The general procedure for the synthesis of 2-amino-5-chloro-2,6-difluorobenzophenone using [4-chloro-2-(2,6-difluorobenzyl)phenyl]-carbamic acid-1,1-dimethylethyl ester as a starting material was as follows: the N-Boc-protected aminobenzophenone was dissolved in anhydrous dichloromethane (50 mL), followed by the addition of trifluoroacetic acid (50 mL). The reaction mixture was stirred for 1 h at room temperature and then the solvent was evaporated to dryness by rotary evaporator under vacuum. The resulting residue was dissolved in a mixture of ethyl acetate (100 mL) and saturated aqueous sodium bicarbonate (100 mL). The organic phase was separated and washed with saturated aqueous sodium bicarbonate solution and subsequently dried with anhydrous magnesium sulfate. The dried organic phase was concentrated to dryness by rotary evaporator and the target product 2-amino-5-chloro-2,6-difluorobenzophenone was quantitatively obtained, and mass spectrometry analysis showed m/z = 268 (M + H).

References

[1] Patent: US2005/256102, 2005, A1. Location in patent: Page/Page column 140
[2] Angewandte Chemie - International Edition, 2012, vol. 51, # 27, p. 6598 - 6603

2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE Suppliers

Canada 1 China 104 Europe 1 India 2 United Kingdom 2 United States 11 Global 121
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE 28910-83-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-19
Career Henan Chemical Co
Product
2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE 28910-83-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-25

28910-83-0, 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONERelated Search:

2,6-DIFLUOROBENZOPHENONE 2-AMINO-2'-FLUOROBENZOPHENONE 2-Amino-5-chloro-2'-fluorobenzophenone tert-butyl 4-chloro-2-(2,6-difluorobenzoyl)phenylcarbamate 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE

  • 2-Amino-5-chloro-2',6'-difluorobenzophenone 98%
  • 2-AMINO-5-CHLORO-2',6'-DIFLUOROBENZOPHENONE
  • 2-AMINO-5-CHLORO-PHENYL-(2-6-DIFLUORO-PHENYL)-METHANONE
  • 2-Amino-5-chloro-2',6'-difluorobenzophenone 98+%
  • 6-benzoyl-4-chloro-1,5-difluorocyclohexa-2,4-dien-1-aMine
  • Methanone, (2-amino-5-chlorophenyl)(2,6-difluorophenyl)-
  • 4-chloro-2-(2,6-difluorobenzoyl)aniline
  • 2-Amino-5-chloro-2′,6′-difluoro-benzophenone, CAS 28910-83-0
  • 28910-83-0
  • C13H8ClF2NO
  • Building Blocks/Intermediates
  • Amines
  • Aromatics