4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
- Product Name
- 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
- CAS No.
- 587850-67-7
- Chemical Name
- 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
- Synonyms
- CS-1909;C7280948;AKOS BBB/007;C7280948, >98%;ASISCHEM B51558;C 7280948;C-7280948;4-AMINO-N-PHENETHYL-BENZENESULFONAMIDE;4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE;Benzenesulfonamide, 4-amino-N-(2-phenylethyl)-;4-Amino-N-(2-phenylethyl)benzenesulfonamide C 7280948
- CBNumber
- CB9493764
- Molecular Formula
- C14H16N2O2S
- Formula Weight
- 276.35
- MOL File
- Mol file
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE Property
- Melting point:
- 143℃
- Boiling point:
- 481.1±55.0 °C(Predicted)
- Density
- 1.258±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL in DMSO
- form
- solid
- pka
- 12.47±0.50(Predicted)
- color
- White to off-white
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- 21601
- Product name
- C-7280948
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 21601
- Product name
- C-7280948
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 21601
- Product name
- C-7280948
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $324
- Updated
- 2024/03/01
- Product number
- 21601
- Product name
- C-7280948
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $575
- Updated
- 2024/03/01
- Product number
- FA113793
- Product name
- 4-Amino-N-(2-phenylethyl)benzenesulfonamide
- Packaging
- 2g
- Price
- $434
- Updated
- 2021/12/16
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE Chemical Properties,Usage,Production
Biological Activity
c7280948 is a novel prmt1 inhibitor with ic50 value of 12.75 μm [1].protein arginine methyltransferase 1 (prmt1) is a histone methyltransferase specific for histone h4. prmt1 catalyzes the transfer of the methyl group from sam to the guanidine nitrogen atoms of arginine residues to produce monomethyl arginines (mma) and asymmetric dimethyl arginines (adma) [2].c7280948 is a novel prmt1 inhibitor. c7280948 interacts with aromatic residues at the hprmt1 substrate binding pocket (tyr 147 and tyr 160) [1]. c7280948 inhibited hprmt1 with ic50 value of 26.7 μm [3].
References
[1]. heinke r, spannhoff a, meier r, et al. virtual screening and biological characterization of novel histone arginine methyltransferase prmt1 inhibitors. chemmedchem, 2009, 4(1): 69-77.
[2]. itoh y, suzuki t, miyata n. small-molecular modulators of cancer-associated epigenetic mechanisms. mol biosyst, 2013, 9(5): 873-896.
[3]. bissinger em, heinke r, spannhoff a, et al. acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hprmt1. bioorg med chem, 2011, 19(12): 3717-3731.
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE manufacturers
- Product
- 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE 587850-67-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- per week:100kg
- Release date
- 2019-09-05