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AMITRIPTYLINE METABOLITE (+/-)-

Product Name
AMITRIPTYLINE METABOLITE (+/-)-
CAS No.
64520-05-4
Chemical Name
AMITRIPTYLINE METABOLITE (+/-)-
Synonyms
10-Hydroxy (E)-Amitriptyline;AMITRIPTYLINE METABOLITE (+/-)-;AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA;Amitriptyline metabolite, (±)-E-10-hydroxylated-;(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol;5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-;(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
CBNumber
CB9496952
Molecular Formula
C20H23NO
Formula Weight
293.4
MOL File
64520-05-4.mol
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AMITRIPTYLINE METABOLITE (+/-)- Property

Melting point:
97-99 °C
Boiling point:
453.3±45.0 °C(Predicted)
Density 
1.151±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
0.1 M HCl: soluble
form 
solid
pka
13.89±0.20(Predicted)
color 
white
Stability:
Hygroscopic
EPA Substance Registry System
5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A115
Product name
Amitriptyline metabolite, (±)-E-10-hydroxylated-
Purity
analytical standard
Packaging
2mg
Price
$310
Updated
2024/03/01
TRC
Product number
D462790
Product name
10-Hydroxy(E)-Amitriptyline
Packaging
10mg
Price
$1605
Updated
2021/12/16
TRC
Product number
D462790
Product name
10-Hydroxy(E)-Amitriptyline
Packaging
25mg
Price
$3550
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0163570
Product name
(+/-)-E-5-[3-(DIMETHYLAMINO)PROPYLIDENE]-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-10-OL
Purity
95.00%
Packaging
5MG
Price
$502.87
Updated
2021/12/16
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AMITRIPTYLINE METABOLITE (+/-)- Chemical Properties,Usage,Production

Uses

(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Definition

ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound.

Biochem/physiol Actions

Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.

AMITRIPTYLINE METABOLITE (+/-)- Preparation Products And Raw materials

Raw materials

Preparation Products

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AMITRIPTYLINE METABOLITE (+/-)- Suppliers

SIGMA-RBI
Tel
--
Fax
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Country
Switzerland
ProdList
6896
Advantage
91

64520-05-4, AMITRIPTYLINE METABOLITE (+/-)-Related Search:


  • (11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
  • AMITRIPTYLINE METABOLITE (+/-)-
  • AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA
  • 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-
  • 10-Hydroxy (E)-Amitriptyline
  • Amitriptyline metabolite, (±)-E-10-hydroxylated-
  • (E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol
  • 64520-05-4