3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one

ChemicalBook > CAS DataBase List > 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one

Synthesis

Product Name: 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one
CAS No.: 66521-54-8
Chemical Name: 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one
Synonyms: 5C-070;511676_ALDRICH;2-[3-(Dimethylamino)acryloyl]pyridine;3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE&;3-(DIMETHYLAMINO)-1-(2-PYRIDYL)-2-PROPE&3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one;1-(2-Pyridyl)-3-dimethylamino-2-propen-1-one;(E)-3-dimethylamino-1-(2-pyridyl)prop-2-en-1-one;3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one;3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one 95%
CBNumber: CB9499498
Molecular Formula: C10H12N2O
Formula Weight: 176.22
MOL File: 66521-54-8.mol

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3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Property

Melting point:: 126-130 °C(lit.)
Boiling point:: 281.4±36.0 °C(Predicted)
Density: 1.07
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 6.25±0.70(Predicted)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 511676
Product name: 3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one
Purity: 95%
Packaging: 25g
Price: $93
Updated: 2023/06/20

TRC

Product number: D495963
Product name: (E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one
Packaging: 5g
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD124317
Product name: (2E)-3-(Dimethylamino)-1-pyridin-2-ylprop-2-en-1-one
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD124317
Product name: (2E)-3-(Dimethylamino)-1-pyridin-2-ylprop-2-en-1-one
Packaging: 1g
Price: $128
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H32-1-27
Product name: 3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one
Purity: 98%
Packaging: 25g
Price: $192
Updated: 2021/12/16

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3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Chemical Properties,Usage,Production

Synthesis

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one was synthesised based on the literature. The reaction of (2g, 16.5mmol) of 2-acetylpyridine and DMF dimethyl acetal(7.84g) were suspended in 11ml of xylene and stir this reaction mixture for 16h at 110℃. Into the resulting mixture 10 ml of hexane added yellow colour precipitate was formed and allows stirring for 20min at 3℃. Resulting mixture was filtered and dried in vacuum to get a yellow colour powder.

Uses

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one may be used in the preparation of the 5-(heteroaryl)isoxazole derivatives, 5-(2-pyridyl)isoxazole and 3-methyl-5-(2-pyridyl)isoxazole. It may also be used to synthesize 7-(2-pyridyl)-1,2,4-triazolo[1,5-a]pyrimidine.

General Description

3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one (1-(2′-Pyridyl)-3-dimethylamino-2-propen-1-one), an enaminone, is a hemilabile hybrid ligand. The preparation of cationic mononuclear rhodium(I) or iridium(I) complexes containing 3-(dimethylamino)-1-(2-pyridyl)-2-propen-1-one have been reported.

3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one Suppliers

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66521-54-8, 3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-oneRelated Search:

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511676_ALDRICH

5C-070

InChI=1/C10H12N2O/c1-12(2)8-6-10(13)9-5-3-4-7-11-9/h3-8H,1-2H3/b8-6

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3-(Dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one

66521-54-8

C9 to C46

Heterocyclic Building Blocks

Pyridines