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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE

Product Name
N-DESMETHYLDILTIAZEM, HYDROCHLORIDE
CAS No.
130606-60-9
Chemical Name
N-DESMETHYLDILTIAZEM, HYDROCHLORIDE
Synonyms
Diltiazem-EP-Imp-D;N-Demethyldiltiazem;Diltiazem Impurity;Diltiazem Impurity D;DiltiazeM EP IMpurity D; N-Monodesmethyldiltiazem;Diltiazem EP Impurity D HCl;N-Desmethyldiltiazem Hydrochloride;(2S,3S)-2-(4-Methoxyphenyl)-5-[2-(m;Diltiazem Impurity 4(Diltiazem EP Impurity D)
CBNumber
CB9500831
Molecular Formula
C21H25ClN2O4S
Formula Weight
436.95
MOL File
130606-60-9.mol
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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Property

Melting point:
156-158°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D291610
Product name
N-DesmethylDiltiazemHydrochloride
Packaging
5mg
Price
$120
Updated
2021/12/16
TRC
Product number
D291610
Product name
N-DesmethylDiltiazemHydrochloride
Packaging
10mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
D3220-87A
Product name
N-Desmethyl Diltiazem Hydrochloride
Packaging
10mg
Price
$460
Updated
2021/12/16
TRC
Product number
D291610
Product name
N-DesmethylDiltiazemHydrochloride
Packaging
100mg
Price
$1355
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0000143
Product name
N-DESMETHYL DILTIAZEM HYDROCHLORIDE
Purity
95.00%
Packaging
100MG
Price
$1593.9
Updated
2021/12/16
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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of diltiazem, an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils

Uses

A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils.

Uses

N-Desmethyl Diltiazem Hydrochloride (Dilitiazem EP Impurity D) is a metabolite of Diltiazem (D460620), an antianginal and an antihypertensive pharmaceutical. Diltiazem regulates calcium release from intracellular stores in neutrophils.

IC 50

CYP3A7

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Suppliers

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130606-60-9, N-DESMETHYLDILTIAZEM, HYDROCHLORIDERelated Search:

O-Desmethyl Diltiazem Hydrochloride 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)- (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride N,N-Didesmethyl Diltiazem Hydrochloride Diltiazem N-Oxide Diltiazem impurity diltiazem hydrochloride Deacetyl-O-demethyl Diltiazem Hydrochloride O-Desacetyl-N-desmethyl Diltiazem Diltiazem Impurity 3 (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 1-oxide DESACETYL DILTIAZEM HCL (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Diltiazem EP Impurity B Diltiazem EP Impurity C Diltiazem hydrochloride DESACETYL DILTIAZEM HYDROCHLORIDE (50 MG) DESMETHYL DILTIAZEM HCL

  • Diltiazem-EP-Imp-D
  • Diltiazem EP Impurity D HCl (N-Desmethyl Diltiazem HCl)
  • Diltiazem Impurity D (N-Desmethyl diltiazem HCl)
  • Diltiazem EP Impurity D HCl
  • N-DemethyldiltiazemN-Monodesmethyldiltiazem,HCl
  • N-Monodesmethyldiltiazem
  • (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride
  • N-Demethyldiltiazem
  • 3-(Acetyloxy)-5-[2-(methylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
  • DiltiazeM EP IMpurity D
  • (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl
  • Diltiazem Impurity 4(Diltiazem EP Impurity D)
  • (2S,3S)-2-(4-Methoxyphenyl)-5-[2-(m
  • 1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-,hydrochloride (1:1), (2S,3S)-
  • Diltiazem EP Impurity D (N-Desmethyl Diltiazem)
  • N-Desmethyl Diltiazem D4 hydrochlorideQ: What is N-Desmethyl Diltiazem D4 hydrochloride Q: What is the CAS Number of N-Desmethyl Diltiazem D4 hydrochloride Q: What is the storage condition of N-Desmethyl Diltiazem D4 hydrochloride Q: What are the applications of N-Desmethyl Diltiazem D4 hydrochloride
  • Diltiazem Hydrochloride Impurity D as Hydrochloride
  • Diltiazem Hydrochloride EP Impurity D as Hydrochloride
  • (2S,3S)-2-(4-Methoxyphenyl)-5-(2-(methylamino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride (Diltiazem Impurity)
  • N-Desmethyldiltiazem Hydrochloride
  • Diltiazem Impurity
  • Diltiazem Impurity D
  • (2S,3S)-2-(4-methoxyphenyl)-5-(2-(methylamino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride
  • (2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-y
  • Diltiazem N-desmethyl hydrochloride 100 μg/mL in Acetonitrile
  • N-Desmethyldiltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)
  • (2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl Acetate Hydrochloride (N-Desmethyl-diltiazem Hydrochloride)
  • 130606-60-9
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals