N-DESMETHYLDILTIAZEM, HYDROCHLORIDE

Product Name: N-DESMETHYLDILTIAZEM, HYDROCHLORIDE
CAS No.: 130606-60-9
Chemical Name: N-DESMETHYLDILTIAZEM, HYDROCHLORIDE
Synonyms: Diltiazem-EP-Imp-D;N-Demethyldiltiazem;Diltiazem Impurity;Diltiazem Impurity D;DiltiazeM EP IMpurity D;N-Monodesmethyldiltiazem;Diltiazem EP Impurity D HCl;N-Desmethyldiltiazem Hydrochloride;(2S,3S)-2-(4-Methoxyphenyl)-5-[2-(m;Diltiazem Impurity 4(Diltiazem EP Impurity D)
CBNumber: CB9500831
Molecular Formula: C21H25ClN2O4S
Formula Weight: 436.95
MOL File: 130606-60-9.mol

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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Property

Melting point:: 156-158°C
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D291610
Product name: N-DesmethylDiltiazemHydrochloride
Packaging: 5mg
Price: $120
Updated: 2021/12/16

TRC

Product number: D291610
Product name: N-DesmethylDiltiazemHydrochloride
Packaging: 10mg
Price: $185
Updated: 2021/12/16

Usbiological

Product number: D3220-87A
Product name: N-Desmethyl Diltiazem Hydrochloride
Packaging: 10mg
Price: $460
Updated: 2021/12/16

TRC

Product number: D291610
Product name: N-DesmethylDiltiazemHydrochloride
Packaging: 100mg
Price: $1355
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21259
Product name: N-Desmethyl diltiazem hydrochloride
Packaging: 5mg
Price: $109.9
Updated: 2021/12/16

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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of diltiazem, an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils

Uses

A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils.

Uses

N-Desmethyl Diltiazem Hydrochloride (Dilitiazem EP Impurity D) is a metabolite of Diltiazem (D460620), an antianginal and an antihypertensive pharmaceutical. Diltiazem regulates calcium release from intracellular stores in neutrophils.

IC 50

CYP3A7

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Suppliers

Canada 1 China 55 Germany 1 India 8 United Kingdom 1 United States 10 Global 76

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

Pharma Affiliates

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Email: @pharmaffiliates.com
Country: India
ProdList: 6754
Advantage: 58

SynZeal Research Pvt Ltd

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Email: standards@synzeal.com
Country: India
ProdList: 6514
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Pharmaffiliates Analytics and Synthetics P. Ltd

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Email: mktg@pharmaffiliates.com
Country: India
ProdList: 6739
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130606-60-9, N-DESMETHYLDILTIAZEM, HYDROCHLORIDERelated Search:

O-Desmethyl Diltiazem Hydrochloride 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)- (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride N,N-Didesmethyl Diltiazem Hydrochloride Diltiazem N-Oxide Diltiazem impurity diltiazem hydrochloride Deacetyl-O-demethyl Diltiazem Hydrochloride O-Desacetyl-N-desmethyl Diltiazem Diltiazem Impurity 3 (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 1-oxide DESACETYL DILTIAZEM HCL (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Diltiazem EP Impurity B Diltiazem EP Impurity C Diltiazem hydrochloride DESACETYL DILTIAZEM HYDROCHLORIDE (50 MG) DESMETHYL DILTIAZEM HCL

Diltiazem-EP-Imp-D

Diltiazem EP Impurity D HCl (N-Desmethyl Diltiazem HCl)

Diltiazem Impurity D (N-Desmethyl diltiazem HCl)

Diltiazem EP Impurity D HCl

N-DemethyldiltiazemN-Monodesmethyldiltiazem,HCl

N-Monodesmethyldiltiazem

(2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one Monohydrochloride

N-Demethyldiltiazem

3-(Acetyloxy)-5-[2-(methylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

DiltiazeM EP IMpurity D

(2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl

Diltiazem Impurity 4(Diltiazem EP Impurity D)

(2S,3S)-2-(4-Methoxyphenyl)-5-[2-(m

1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-,hydrochloride (1:1), (2S,3S)-

Diltiazem EP Impurity D (N-Desmethyl Diltiazem)

N-Desmethyl Diltiazem D4 hydrochlorideQ: What is N-Desmethyl Diltiazem D4 hydrochloride Q: What is the CAS Number of N-Desmethyl Diltiazem D4 hydrochloride Q: What is the storage condition of N-Desmethyl Diltiazem D4 hydrochloride Q: What are the applications of N-Desmethyl Diltiazem D4 hydrochloride

Diltiazem Hydrochloride Impurity D as Hydrochloride

Diltiazem Hydrochloride EP Impurity D as Hydrochloride

(2S,3S)-2-(4-Methoxyphenyl)-5-(2-(methylamino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride (Diltiazem Impurity)

N-Desmethyldiltiazem Hydrochloride

Diltiazem Impurity

Diltiazem Impurity D

(2S,3S)-2-(4-methoxyphenyl)-5-(2-(methylamino)ethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride

(2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-y

Diltiazem N-desmethyl hydrochloride 100 μg/mL in Acetonitrile

N-Desmethyldiltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)

(2S,3S)-2-(4-Methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl Acetate Hydrochloride (N-Desmethyl-diltiazem Hydrochloride)

130606-60-9

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals