TH 257

Product Name: TH 257
CAS No.: 2244678-29-1
Chemical Name: TH 257
Synonyms: TH 257;TH-257, 10 mM in DMSO;N-Benzyl-N-butyl-4-(N-phenylsulfamoyl)benzamide;LIM Kinase (LIMK),LIMKs,Inhibitor,TH-257,inhibit,TH257;Benzamide, N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-
CBNumber: CB95476799
Molecular Formula: C24H26N2O3S
Formula Weight: 422.54
MOL File: 2244678-29-1.mol

More

Less

TH 257 Property

storage temp.: 2-8°C
solubility: DMSO:42.25(Max Conc. mg/mL);100.0(Max Conc. mM)
Ethanol:42.25(Max Conc. mg/mL);100.0(Max Conc. mM)
form: powder
color: white to beige

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0087663
Product name: TH-257
Purity: 98.91%
Packaging: 10mg
Price: $113
Updated: 2021/12/16

Axon Medchem

Product number: Axon2973
Product name: TH257
Purity: 99%
Packaging: 50mg
Price: $368.5
Updated: 2021/12/16

ChemScene

Product number: CS-0087663
Product name: TH-257
Purity: 98.91%
Packaging: 5mg
Price: $73
Updated: 2021/12/16

Ambeed

Product number: A1193405
Product name: N-Benzyl-N-butyl-4-(N-phenylsulfamoyl)benzamide
Purity: 98+%
Packaging: 5mg
Price: $93
Updated: 2021/12/16

CSNpharm

Product number: CSN24750
Product name: TH257
Packaging: 1mg
Price: $27
Updated: 2021/12/16

More

Less

TH 257 Chemical Properties,Usage,Production

Biological Activity

TH-257 is a potent, type III allosteric LIM-kinase (LIMK1 & LIMK2) inhibitor (LIMK1/2 IC50 in nM = 48/29 by cell-free kinase assay and 250/150 by live cell NanoBRET assay using respective transfectants) th at targets LIMK1/2 DFG-out conformation in a non-ATP-competitive manner and exhibits no significant off-target activity by KINOMEscan assay at 1 μM. TH-263 is a structure analog and the recommended negative control for TH-257. For characterization details of TH-257, please visit the TH-257 probe summary on the Structural Genomics Consortium (SGC) website.

TH-263 is the negative control for the active probe, TH-257. TH-263 is available from Sigma. To learn more about and purchase TH-263, click here.

To learn about other SGC chemical probes, visit sigma.com/sgc

storage

Store at +4°C

TH 257 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

TH 257 Suppliers

China 41 United States 6 Global 47

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4588
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9804
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7328
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29764
Advantage: 68

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1471
Advantage: 58

2244678-29-1, TH 257Related Search:

TH 257

Benzamide, N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-

LIM Kinase (LIMK),LIMKs,Inhibitor,TH-257,inhibit,TH257

N-Benzyl-N-butyl-4-(N-phenylsulfamoyl)benzamide

TH-257, 10 mM in DMSO

2244678-29-1