ChemicalBook > CAS DataBase List > BPK-29 hydrochloride
BPK-29 hydrochloride
- Product Name
- BPK-29 hydrochloride
- CAS No.
- 2444815-73-8
- Chemical Name
- BPK-29 hydrochloride
- Synonyms
- BPK-29 hcl;BPK-29 hydrochloride;BPK-29 hydrochloride, 10 mM in DMSO;inhibit,BPK 29,BPK29,BPK-29,Inhibitor,BPK 29 hydrochloride,BPK29 hydrochloride
- CBNumber
- CB95559122
- Molecular Formula
- C26H33Cl2N3O3
- Formula Weight
- 506.47
- MOL File
- 2444815-73-8.mol
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BPK-29 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: 62.5 mg/mL (123.41 mM)
- form
- Solid
- color
- White to off-white
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BPK-29 hydrochloride Chemical Properties,Usage,Production
Description
BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 hydrochloride impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].
BPK-29 hydrochloride substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].
References
[1]. Bar-Peled L, et al. Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. Cell. 2017 Oct 19;171(3):696-709.e23.
BPK-29 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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BPK-29 hydrochloride Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
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- Advantage
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